Comparison of simplified and traditional pericardial devascularisation combined with splenectomy for the treatment of portal hypertension

Table 1 Comparison of clinical characteristics n (%)

Parameters	S Group (n = 357)	T Group (n = 688)	Statistic	P-value
Gender, male	196 (54.90)	368/320 (53.49)	χ2 = 0.19	0.66
Age (yr)	47.68 ± 11.71	47.13 ± 11.98	t = 0.71	0.48
Aetiology			χ2 = 7.52	0.11
Hepatitis B	261 (73.11)	454 (65.99)
Hepatitis C	39 (10.92)	82 (11.92)
Autoimmune hepatitis	9 (2.52)	33 (4.80)
Nonspecific hepatitis	40 (11.20)	94 (13.66)
Others	8 (2.24)	25 (3.63)
History of abdominal surgery	81 (22.69)	183 (26.60)	χ2 = 1.90	0.17
History of variceal bleeding	181 (50.70)	388 (56.40)	χ2 = 3.07	0.08
Ascites	268 (75.07)	490 (71.22)	χ2 = 1.75	0.19
Child-Pugh grade at admission			χ2 = 8.60	0.01
A	153 (42.86)	359 (52.18)
B	188 (52.66)	300 (43.60)
C	16 (4.48)	29 (4.22)
Oesophageal varices grade			χ2 = 0.30	0.86
Mild	44 (12.32)	93 (13.52)
Moderate	114 (31.93)	219 (31.83)
Severe	199 (55.74)	376 (54.65)
PHG at admission	118 (33.05)	172 (25.00)	χ2 = 7.60	< 0.05
Preoperative MELD score	5.97 ± 0.40	5.95 ± 0.40	t = 0.61	0.54
Preoperative portal vein diameter (cm)	1.53 ± 1.52	1.39 ± 0.43	t = 0.86	0.4

MELD: Model for end-stage liver disease.

Table 2 Comparison of perioperative indicators

Parameters	S Group (n = 357)	T Group (n = 688)	Statistic	P-value
Postoperative hospital stay (d)	10.70 ± 5.35	14.96 ± 5.66	t = -3.64	< 0.05
Operation fee (Yuan)	3638.85 ± 1144.17	4168.06 ± 960.53	t = 3.60	< 0.05
Total hospitalisation cost (Yuan)	29654.60 ± 17475.10	35331.13 ± 18165.41	t = 2.67	0.01
Operative time (min)	125.60 ± 46.08	144.83 ± 54.06	t = 3.96	< 0.05
Intraoperative blood loss (mL)	291.46 ± 208.86	573.42 ± 409.38	t = 4.76	< 0.05
Intraoperative transfusion (mL)	700.82 ± 541.92	986.60 ± 627.75	t = 5.30	< 0.05
Time to first flatus (d)	3.74 ± 1.21	4.61 ± 1.60	t = -7.83	< 0.05
Mortality	0	4
Reoperation	0	1

Table 3 Comparison of short-term and long-term recovery indicators and complications after the operation n (%)

Parameters	S Group (n = 357)	T Group (n = 688)	Statistic	P-value
Short-term portal vein diameter (cm)	1.27 ± 0.18	1.28 ± 0.20	t = -0.07	0.94
Long-term portal vein diameter (cm)	1.13 ± 0.141	1.16 ± 0.171	t = -1.16	0.25
Short-term MELD score	5.88 ± 0.54	5.97 ± 0.48	t = -1.39	0.16
Long-term MELD score	5.79 ± 0.501	5.78 ± 0.421	t = 0.27	0.79
Short-term complications
Ascites	105 (29.41)	298 (43.31)	χ2 = 19.17	< 0.05
Portal vein thrombosis	49 (13.73)	153 (22.24)	χ2 = 10.92	< 0.05
Pleural effusion	66 (18.49)	271 (39.39)	χ2 = 47.00	< 0.05
Wound infections	10 (2.80)	37 (5.38)	χ2 = 3.63	0.06
Hepatic encephalopathy	3 (0.84)	5 (0.73)	χ2 = 0.04	1
Rebleeding	0 (0.00)	3 (0.44)	χ2 = 1.56	0.56
Long-term complications
Ascites	36 (10.08)	122 (17.73)	χ2 = 10.71	< 0.05
Portal vein thrombosis	25 (7.00)	78 (11.34)	χ2 = 4.97	0.03
Pleural effusion	57 (15.97)	95 (13.81)	χ2 = 0.88	0.35
Hepatic encephalopathy	3 (0.84)	7 (1.02)	χ2 = 0.08	1
Rebleeding	21 (5.88)	89 (12.94)	χ2 = 12.42	< 0.05

¹A significant difference compared with the preoperative and short-term parameters. MELD: Model for end-stage liver disease.