Possible connection between elevated serum α-fetoprotein and placental necrosis during pregnancy: A case report and review of literature

Table 1 Prenatal clinical laboratory data of the patient

Name	Items	Result	Reference range
Blood routine examination	WBC	13.79 × 109/L	3.50-9.50 × 109/L
	LY	0.84 × 109/L	1.10-3.20 × 109/L
	MO	0.43 × 109/L	0.10-0.60 × 109/L
	NE	12.50 × 109/L	1.80-6.30 × 109/L
	EO	0.00 × 109/L	0.02-0.52 × 109/L
	BA	0.02 × 109/L	0.00-0.06 × 109/L
	RBC	2.98 × 1012/L	3.80-5.10 × 1012/L
	HGB	90 g/L	115-150 g/L
	PLT	212 × 109/L	125-350 × 109/L
	CRP	12.00 mg/L	0-8 mg/L
Coagulation function tests	PT	11.80 s	11 ± 3 s
	INR	0.98	-
	APTT	19.10 s	24.5 ± 10 s
	FIB	2.44 g/L	2.0-4.0 g/L
	TT	15.90 s	18 ± 3 s
	D-D	1.08 mg/L	< 0.55 mg/L
Biochemistry examination	HbA1c	4.90%	4.0-6.4 %
	ALT	15.7 U/L	7-40 U/L
	AST	20.3 U/L	13-35 U/L
Thyroid function tests	FT3	2.94 pmol/L	3.10-6.80 pmol/L
	TSH	1.09 mIU/L	0.27-4.20 mIU/L
	FT4	14.23 pmol/L	12.00-22.00 pmol/L
Tumor markers	AFP	1032.00 ng/mL	< 20.0 ng/mL
	CEA	0.43 ng/mL	< 4.7 ng/mL
	CA125	168.20 U/mL	< 35.0 U/mL
	CA199	26.47 U/mL	< 27.0 U/mL
	NSE	17.05 ng/mL	< 16.3 ng/mL

WBC: White blood cell; LY: Lymphocyte; MO: Monocyte; NE: Neutrophilic; ECO: Eosinophil; BA: Basophil; RBC: Red blood cell; HGB: Hemoglobin; PLT: Platelet; CRP: C-reactive protein; PT: Prothrombin time; INR: International normalized ratio; APTT: Activated partial thromboplastin time; FIB: Fibrinogen; TT: Thrombin time; D-D: D-dimer; HbA1c: Glycated hemoglobin; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; FT3: Free triiodothyronine; TSH: Thyroid stimulating hormone; FT4: Free thyroxine; AFP: α-fetoprotein; CEA: Carcinoembryonic antigen; CA125: Carbohydrate antigen 125; CA199: Carbohydrate antigen 199; NSE: Neuron-specific enolase.