Dengue and its effects on liver

Table 1 Liver function abnormalities in dengue patients

Ref.	Patients	Raised AST	Raised ALT	AST > ALT	Hyper-bilirubinemia	> 10 fold rise (AST, ALT)
Kuo et al[37]	270	93.30%	82.20%	+	7.20%	11.1%, 7.4%
Souza et al[39]	1585	63.40%	45%	+	-	3.4%, 1.8%
Itha et al[41]	45	96%	96%	Equal	30%	-
Wong et al[40]	127	90.60%	71.70%	+ in 75.6%	13.4%	10.2%, 9.5%
Parkash et al[33]	699	95%	86%	+	-	15%
Trung et al[36]	644	97%	97%	+	1.7%	-
Lee et al[14]	690	86%	46%	-	-	1%
Karoli et al[34]	138	92%		+	48%	-
Saha et al[35]	1226				16.9%

AST: Aspartate transaminase; ALT: Alanine transaminase.

Table 2 Liver function abnormalities among children with dengue

Ref.	Patients (n)	Raised AST/ALT	Hepatomegaly	Jaundice	Hypoalbuminemia
Pires Neto Rda et al[45]	32	96%	37.50%	-	77%
Mohan et al[44]	61	87%	74%	25%	-
Jagadishkumar et al[46]	110	-	79%	4.50%	66%
Kulkarni et al[47]	948	90%	36.70%	0.95%	-
Roy et al[48]	120	94%	80.80%	60%	-

AST: Aspartate transaminase; ALT: Alanine transaminase.