Small cell lung cancer with peripheral neuropathy as the first symptom: Two case reports

Table 1 Electromyography/evoked potential test report of Case 1, sensory nerve conduction

Nerve/position	Latent period, ms	Amplitude, μV	Conduction velocity, m/s	Distance, mm
L median nerve
Finger 3	3.23	5.8	44	141
Finger 4	3.39	7.8
R median nerve
Finger 3	3.18	5.5	41	130
Finger 4	3.28	4.2
L ulnar nerve
Finger 5	1.93	6.5	60	116
Finger 4	1.98	6.5
R ulnar nerve
Finger 5	1.93	5.3	57	109
Finger 4	2.03	6.9
R nervi suralis
Gastrocnemius	1.93	3.9	49	95
L nervi suralis
Gastrocnemius	2.55	4.3	50	127
R superficial peroneal nerve
Calf	2.19	4.8	46	100
L superficial peroneal nerve
Calf	2.08	4.6	43	90

L: Left; R: Right.

Table 2 Electromyography/evoked potential test report of Case 1, motor nerve conduction

Nerve/position	Recording position	Latent period, ms	Amplitude, μV	Conduction velocity, m/s	Distance, mm
L median nerve
Wrist	Abductor pollicis brevis muscle	3.8	4.26
Elbow	Abductor pollicis brevis muscle	8.07	4.03	51	217
R median nerve
Wrist	Abductor pollicis brevis muscle	4.01	4.15
Elbow	Abductor pollicis brevis muscle	8.02	3.98	50	200
L ulnar nerve
Wrist	Abductor digiti minimi	2.97	7.24
Below the elbow	Abductor digiti minimi	6.56	6.47	54	195
R ulnar nerve
Wrist	Abductor digiti minimi	2.97	7.58
below the elbow	Abductor digiti minimi	6.77	7.16	53	200
R peroneal nerve
Ankle	Extensor digitorum brevis	3.23	1.06
Under the capitulum of fibula	Extensor digitorum brevis	10.57	0.97	41	300
L peroneal nerve
Ankle	Extensor digitorum brevis	3.44	2.44
Under the capitulum of fibula	Extensor digitorum brevis	10.10	1.95	44	295
R tibial nerve
Ankle	Abductor hallucis	3.59	4.17
Popliteal fossa	Abductor hallucis	12.92	4.15	40	370
L tibial nerve
Ankle	Abductor hallucis	3.59	4.16
Popliteal fossa	Abductor hallucis	12.66	3.05	41	376

L: Left; R: Right.

Table 3 Electromyography/evoked potential test report of Case 1, F-wave

Nerve	Min M reaction time, ms	Mean M reaction time, ms	Min F reaction time, ms	Mean F reaction time, ms	F-wave occurrence rate, %
L ulnar nerve	2.9	2.9	28.2	28.9	100
R ulnar nerve	2.9	3.0	28.8	29.5	100
R tibial nerve	3.6	3.7	55.0	57.8	100
L tibial nerve	3.8	3.8	53.3	57.2	100

Diagnostic opinion: Electrophysiological findings of multiple peripheral neuropathies involving axonal damage to the motor and sensory nerves of the upper and lower extremities. Bilateral median nerves were damaged at the wrist, and the electrophysiological manifestations of bilateral carpal tunnel syndrome were mild. L: Left; R: Right.

Table 4 Electromyography/evoked potential test report from case 2, sensory nerve conduction

Nerve/position	Latent period, ms	Amplitude, μV	Conduction velocity, m/s	Distance, mm
R median nerve
Finger 3	2.97	5.5	39	117
R ulnar nerve
Finger 5	2.34	5.0	44	103
L nervi suralis
Gastrocnemius	2.19	7.7	32	70
R nervi suralis
Gastrocnemius	2.34	6.0	38	90
R superficial peroneal nerve
Calf	2.34	5.8	36	85
L superficial peroneal nerve
Calf	2.34	5.5	34	80

L: Left; R: Right.

Table 5 Electromyography/evoked potential test report from Case 2, motor nerve conduction

Nerve/position	Recording position	Latent period, ms	Amplitude, μV	Conduction velocity, m/s	Distance, mm
R median nerve
Wrist	Abductor pollicis brevis muscle	3.33	6.0
Elbow	Abductor pollicis brevis muscle	7.50	5.5	54	225
R ulnar nerve
Wrist	Abductor digiti minimi	2.34	10.2
Below the elbow	Abductor digiti minimi	6.51	9.2	54	225
R peroneal nerve
Ankle	Extensor digitorum brevis	3.23	4.4
Under the capitulum of fibula	Extensor digitorum brevis	9.32	3.6	42	257
L peroneal nerve
Ankle	Extensor digitorum brevis	3.33	2.7
Under the capitulum of fibula	Extensor digitorum brevis	9.74	2.3	41	260
L tibial nerve
Ankle	Abductor hallucis	3.44	12.6
Popliteal fossa	Abductor hallucis	12.24	8.4	40	350
R tibial nerve
Ankle	Abductor hallucis	3.59	14.4
Popliteal fossa	Abductor hallucis	11.82	9.8	42	345

Diagnostic opinion: Electrophysiological changes of multiple peripheral nerve lesions involving the sensory nerves of the upper and lower limbs with demyelinating lesions. L: Left; R: Right.