Merkel cell carcinoma presenting as a nasal dorsum mass: A case report and literature review

Table 1 List of published cases on Merkel cell carcinoma in comparison with the current case report

Ref.	Age (years)	Sex	Comorbid condition	Management	Post-surgical complications	Lymph nodes involvement	Follow up duration/ outcome
Swanson et al[12]	56	Male	None	Bilateral supraomohyoid neck dissection with adjuvant radiotherapy	None	None	At 30-month follow-up, magnetic resonance imaging and computed tomography showed no locoregional recurrence
De Sousa Machado et al[13]	83	Female	None	Tumor excision	None	None	This patient had surgery only and remained disease-free for over 10 years
Nagase et al[14]	63	Female	None	Tumor excision + bilateral neck dissection + adjuvant chemotherapy(etoposide) and radiotherapy	Acute necrotic pancreatitis and chronic cholecystitis	Cervical and supracervical	The patient was last hospitalized in September 2008 for pneumonia and died 17 months after Merkel cell carcinoma diagnosis due to rapid health decline
Rocamora et al[15]	79	Male	None	Paramedian forehead nasal flap and right supraomohyoid neck dissection+ adjuvant radiotherapy	None	Right neck level 1 sentinel node	No evidence of disease at 16 months follow-up postoperatively
Gessner et al[16]	61	Male	History of basal cell carcinoma	Tumor excision	None	Regional lymph nodes involvement	At 18 months, the patient was well with no signs of local or systemic disease
Zeitouni et al[17]	78	Female	Well controlled chronic lymphatic leukemia and asthma	Wide excision of the tumor involving the nasal tip, dorsum of the left side of the nose, and adjacent cheek, with clearance up to the periosteum of the maxilla + skin grafting was performed after the excision with adjuvant radiotherapy	Left parotic mass	Enlarged lymph nodes behind the left jaw angle operation, enlarged left neck lymph node	Currently under follow-up with no clinical evidence of residual disease
This case	65	Female	Hypertension, diabetes mellitus	Paramedian forehead nasal flap + modified radical neck dissection + adjuvant radiotherapy of 30 sessions	None	Right level 1B, left level 2B and 2A	No clinical evidence of residual disease after 6 months follow-up