Acute pancreatitis as a complication of acute COVID-19 in kidney transplant recipients

Table 1 Coronavirus disease 2019 kidney transplant recipients characteristics (n = 321)

Characteristics	Number (%) of patients	Range
Sex
Male/female	183/138 (57/43)
Age (yr) [Median (IQR)] Primary kidney disease	55 (44-64)	22-81
Glomerulonephritis	9 + 8 (30.6)
Diabetic nephropathy	12 (3.8)
ADPKD	48 (15)
Pyelonephritis	26 (8.1)
Nephroangiosclerosis	26 (8.1)
Other	110 (34.4)
Time from transplantation (months) [Median (IQR)]	94.5 (52-135.8)	1-368
Height (cm) [Median (IQR)]	171 (163-180)	124-199
Body weight (kg) [Median (IQR)]	79 (67-92)	42-150
BMI [Median (IQR)]	26.5 (23.9-29.2)	17.36-45.79
Nutritional status
Underweight (BMI < 18.5)	4 (1.3)
Normal weight	105 (32.8)
Pre-obesity (25-29.9)	144 (45)
Obese (≥ 30)	67 (20.9)
Previous thrombosis	30 (9.4)
Previous myocardial infarction or stroke	32 (10)
Previous CMV infection	36 (11.3)
Previous BK infection	68 (21.3)
Previous EBV infection	28 (8.8)
Allograft rejection	46 (14.4)
Creatinine value [Median (IQR)]	129 (98-165.8)	45-430
CKD EPI [Median (IQR)]	49 (35-64)	0.23-133
Biuret [Median (IQR)]	0.2 (0.1-0.5)	0-79
Vaccinated against COVID-19	246 (76.9)
Before COVID-19 infection	149 (46.6)
After COVID-19 infection	97 (30.3)
Number of vaccine doses [Median (IQR)]	2 (2-3)	1-4
Number of vaccine doses (n = 246)
One	21 (8.5)
Two	138 (56.1)
Three	83 (33.7)
Four	4 (1.6)
COVID-19 initial symptoms
Febrility	245 (76.6)
Diarrhea	39 (12.2)
Respiratory	230 (71.9)
Asymptomatic	21 (6.6)
COVID-19 initial complications
Hospitalisation	125 (39.1)
Pneumonia	141 (44.1)
Mechanical ventilation	4 (1.3)
Other	66 (20.6)
Initial immunosuppression
Tacrolimus	222 (69.4)
Cyclosporin A	70 (21.9)
Mycophenolate	280 (87.5)
Azathioprine	12 (3.8)
Everolimus	48 (15)
Prednisolone (dose) [Median (IQR)]	5 (5-5)	0-30
Acute COVID-19 treatment
Cessation of MMF/Aza	133 (41.6)
Decreasing MMF/Aza	102 (31.9)
Cessation of Tac/CyA	1 (0.3)
Decreasing Tac/CyA	29 (9.1)
Hyperimmune anti-CMV globulin	30 (9.4)
Intravenous immunoglobulin	13 (4.4)

COVID-19: Coronavirus disease 2019; ADPKD: Autosomal dominant polycystic kidney disease; CMV: Cytomegalovirus; EBV: Epstein-Barr virus; BKV: BK virus; MMF: Mycophenolate mofetil; Aza: Azathioprine; CyA: Cyclosporine; Tac: Tacrolimus; BMI: Body mass index.