Incidental renal cell carcinoma post bilateral nephrectomy in autosomal dominant polycystic kidney disease

Table 1 Characteristics of patients with autosomal dominant polycystic kidney disease who underwent bilateral nephrectomy, n (%)

Characteristics	Patients
Age (years) (mean ± SD)	56.8 ± 5.71
Sex (male/female)	14/5
Comorbidity
Hypertension	17 (89.5)
Diabetes mellitus	6 (31.6)
Cerebrovascular accident	3 (15.8)
Cardiovascular disease	4 (21.1)
Arrhythmia	2 (10.5)
Chronic obstructive pulmonary disease	1 (5.3)
American society of anesthesiologists physical status grade
3	17 (89.5)
4	2 (10.5)
Reason for nephrectomy
Hematuria	3 (15.8)
Infection	1 (5.3)
Gastrointestinal symptoms	13 (68.4)
Suspicious of renal cell carcinoma	2 (10.5)
Duration of hemodialysis (months) (mean ± SD)	84.2 ± 89.58
Largest diameter of kidney (cm) (mean ± SD)	16.1 ± 6.46
Type of surgery
Open	8 (42.1)
Hand-assisted laparoscopic surgery	11 (57.9)
Length of hospital stay (days) (mean ± SD)	17.1 ± 6.1
Follow-up period after nephrectomy (months) (mean ± SD)	28.1 ± 20.40

Table 2 Characteristics of patients with renal cell carcinoma

	Patient 1	Patient 2	Patient 3	Patient 4
Age (years)	56	50	53	56
Sex	Male	Male	Male	Male
Reason of nephrectomy	GI symptoms	Frequent infection	GI symptoms	Suspicious RCC on ultrasonographic
Bilaterality	Yes	No	No	Yes
Multifocality	Yes	No	No	Yes
Histology	Tubulopapillary carcinomas	Clear cell carcinoma	Tubulopapillary carcinomas	Tubulopapillary carcinomas
Diameter of RCC (cm)	1.2 × 1.0 and 1.3 × 1.0	2.6 × 1.5	1.8 × 1.6	1.5 × 1.0 and 1.5 × 0.5
Duration of hemodialysis (months)	175	159	7	101

RCC: Renal cell carcinoma; GI: Gastrointestinal.

Table 3 Comparison between patients with and without renal cell carcinoma, n (%)

	With RCC	Without RCC	P value
Age (years) (mean ± SD)	53.8 ± 2.87	57.6 ± 6.07	0.097
Sex (male)	4 (100)	10 (66.7)	0.530
Comorbidity
Hypertension	4 (100)	13 (86.7)	1.0
Diabetes mellitus	1 (25.0)	5 (33.3)	1.0
Cerebrovascular accident	0	4 (26.7)	0.530
Cardiovascular disease	0	4 (26.7)	0.530
Arrhythmia	0	2 (13.3)	1.0
Chronic obstructive pulmonary disease	0	1 (6.7)	1.0
American society of anesthesiologists physical status grade			1.0
3	4 (100)	13 (86.7)
4	0	2 (13.3)
Reason for nephrectomy			0.118
Hematuria	0	3 (20)
Infection	1 (25)	0
Gastrointestinal symptoms	2 (50)	11 (73.3)
Suspicious of RCC	1 (25)	1 (6.7)
Duration of hemodialysis (months)	110.5 ± 75.97	77.2 ± 93.97	0.368
Type of surgery			0.603
Open	1 (25)	7 (46.7)
Hand-assisted laparoscopic surgery	3 (75)	9 (53.3)
Length of hospital stay (days)	13.2 ± 6.70	18.1 ± 5.73	0.160
Follow-up period after nephrectomy (months)	26.2 ± 7.09	28.6 ± 22.86	0.841
Largest kidney diameter (cm)	14.1 ± 6.05	16.5 ± 6.56	0.522

RCC: Renal cell carcinoma.