Effectiveness of onsite and online education in enhancing knowledge and use of human immunodeficiency virus pre- and post-exposure prophylaxis

Table 1 Baseline demographic and sexual behavior characteristics of participants in Beijing

Variables	Frequency, n = 112	%
Age in yr
20-30	49	43.7
31-40	44	39.3
41-50	15	13.4
51-60	4	3.6
Sex
Male	109	97.3
Female	3	2.7
Education level
High school or below	16	14.3
College and undergraduate	68	60.7
Postgraduate or above	28	25
Monthly expenditure in RMB
Less than 1000	8	7.5
1000-2999	25	22.6
3000-4999	20	17
5000 and above	59	51.9
Sexual orientation
Heterosexual	29	25.9
Homosexual	69	61.6
Bisexual	14	12.5
History of STD
Yes	16	14.3
No	96	85.7
History of drug use
Yes	10	8.9
No	102	91.1

STD: Sexually transmitted disease.

Table 2 Comparison of knowledge of and willingness to use human immunodeficiency virus pre-exposure prophylaxis before and after intervention

Variable	Before intervention	After intervention	χ²	P value
	n = 112, n (%)	n = 105, n (%)
Knowledge level of PrEP			8.846	0.003
Good	73 (65.2)	88 (83.8)
Poor	39 (34.8)	17 (16.2)
Willingness to use PrEP			4.556	0.033
Yes	78 (69.6)	87 (82.9)
No	34 (30.4)	18 (17.1)

PrEP: Pre-exposure prophylaxis.

Table 3 Comparison of knowledge of and willingness to use human immunodeficiency virus post-exposure prophylaxis before and after intervention

Variable	Before intervention	After intervention	χ²	P value
	n = 112, n (%)	n =105, n (%)
Knowledge level of PEP			11.574	0.001
Good	83 (74.1)	97 (92.4)
Poor	29 (25.9)	8 (7.6)
Willingness to use PEP			4.634	0.031
Yes	87 (77.7)	94 (89.5)
No	25 (22.3)	11 (10.5)

PEP: Post-exposure prophylaxis.

Table 4 Factors associated with knowledge of pre-exposure prophylaxis

Parameters	OR (95%CI)	P value	AOR (95%CI)	P value
Age in yr
20-30	Reference category
31-40	0.326 (0.114, 0.929)	0.036a	0.268 (0.088, 0.817)	0.021a
41-50	0.147 (0.018, 1.221)	0.147	0.335 (0.082, 1.375)	0.129
51-60	2.062 (0.266, 16.004)	0.489	1.779 (0.303, 10.430)	0.523
Sex
Male	Reference category
Female	4.253 (0.252, 71.662)	0.550	1.938 (0.128, 29.374)	0.633
Education level
High school or below	Reference category
College and undergraduate	0.920 (0.191, 4.432)	0.917	0.325 (0.089, 1.181)	0.088
Postgraduate or above	0.131 (0.023, 0.757)	0.023a	0.196 (0.044, 0.873)	0.032a
Monthly expenditure in RMB
Less than 1000	Reference category
1000-2999	0.706 (0.170, 2.923)	0.631	0.511 (0.085, 3.086)	0.464
3000-4999	0.447 (0.119, 1.669)	0.231	0.747 (0.121, 4.628)	0.754
5000 and above	0.126 (0.019, 0.827)	0.031a	0.142 (0.024, 0.850)	0.035a
Sexual orientation
Heterosexual	Reference category
Homosexual	0.650 (0.197, 2.138)	0.478	0.986 (0.324, 3.006)	0.981
Bisexual	1.625 (0.326, 8.095)	0.553	1.785 (0.223, 14.275)	0.585
History of STD
Yes	Reference category
No	1.445 (0.255, 8.205)	0.678	1.027 (0.259, 4.075)	0.970
History of drug use
Yes	Reference category
No	0.540 (0.104, 2.798)	0.463	0.769 (0.121, 4.870)	0.780

^aP < 0.05. STD: Sexually transmitted disease.

Table 5 Factors associated with knowledge of post-exposure prophylaxis

Factors	OR (95%CI)	P value	AOR (95%CI)	P value
Age in yr
20-30	Reference category
31-40	0.210 (0.045, 0.983)	0.047a	0.167 (0.033, 0.842)	0.030a
41-50	0.671 (0.143, 3.151)	0.613	0.886 (0.212, 3.708)	0.869
51-60	1.857 (0.168, 20.511)	0.615	1.147 (0.365, 3.601)	0.814
Sex
Male	Reference category
Female	11.940 (0.523, 272.777)	0.120	10.813 (0.460, 254.122)	0.139
Education level
High school or below	Reference category
College and undergraduate	0.591 (0.126, 2.781)	0.506	0.564 (0.127, 2.499)	0.451
Postgraduate or above	0.045 (0.003, 0.678)	0.025a	0.103 (0.021, 0.513)	0.005a
Monthly expenditure in RMB
Less than 1000	Reference category
1000-2999	0.394 (0.055, 2.815)	0.353	0.435 (0.095, 1.996)	0.435
3000-4999	0.421 (0.070, 2.550)	0.347	0.473 (0.147, 1.522)	0.209
5000 and above	0.101 (0.016, 0.654)	0.016a	0.140 (0.028, 0.690)	0.017a
Sexual orientation
Heterosexual	Reference category
Homosexual	0.424 (0.056, 3.215)	0.262	0.460 (0.063, 3.356)	0.444
Bisexual	1.815 (0.366, 8.996)	0.462	1.487 (0.187, 11.808)	0.708
History of STD
Yes	Reference category
No	3.264 (0.361, 29.482)	0.292	2.221 (0.260, 18.957)	0.466
History of drug use
Yes	Reference category
No	0.832 (0.122, 5.656)	0.851	0.804 (0.122, 5.308)	0.821

^aP < 0.05. STD: Sexually transmitted disease.