Establishment of a nomogram model for predicting therapy complications in patients with polycythemia and deep venous thrombosis

Table 1 Univariate analysis of factors affecting thrombotic recurrence in patients with high-altitude polycythemia and lower-extremity deep venous thrombosis

Factor	Group	Recurrence group (n = 33)	Non-recurrence group (n = 80)	χ2/t	P value
Age (year)				7.646	0.006
	< 60	13	54
	≥ 60	20	26
Sex				0.039	0.843
	Male	18	42
	Female	15	38
Smoking history				0.184	0.668
	Yes	7	20
	No	26	60
Alcohol consumption history				0.136	0.713
	Yes	6	17
	No	27	63
Education level				1.221	0.543
	Primary or below	7	13
	Middle school level	20	45
	Junior college or above	6	22
Residence				2.091	0.148
	Urban areas	10	36
	Rural areas	23	44
Complicated with malignant tumor				0.001	0.970
	Yes	2	5
	No	31	75
Breaking history				14.152	< 0.001
	Yes	7	1
	No	26	79
Medication compliance				11.502	< 0.001
	Good	17	66
	Poor	16	14
Compliance with wearing elastic stockings				9.184	0.002
	Good	20	69
	Poor	13	11
D-D (mg/L)		1.26 ± 0.31	0.41 ± 0.11	21.512	< 0.001
RBC (× 1012/L)		4.96 ± 0.85	4.99 ± 1.02	0.146	0.884
WBC (× 109/L)		6.51 ± 0.79	6.49 ± 0.83	0.118	0.906
PLT (× 109/L)		187.44 ± 33.57	189.37 ± 31.58	0.290	0.772
PT (second)		13.77 ± 1.81	13.68 ± 1.75	0.243	0.808
ATPP (second)		30.45 ± 2.89	31.07 ± 3.54	0.890	0.375
TT (second)		18.44 ± 2.03	18.73 ± 2.17	0.658	0.512
FIB (g/L)		2.83 ± 0.39	2.86 ± 0.43	0.346	0.730
FDP (mg/L)		4.84 ± 1.07	4.17 ± 1.12	2.925	0.004

ATPP: Activated partial thromboplastin time; D-D: D-dimer; FDP: Fibrin degradation product; FIB: Fibrinogen; PLT: Platelet; PT: Prothrombin time; RBC: Red blood cell; TT: Thrombin time; WBC: White blood cell.

Table 2 Assignment table

Variable	Variable name	Assignments
Y	Thrombosis recurrence	No = 0, Yes = 1
X1	Age (year)	< 60 = 0, ≥ 60 = 1
X2	Braking during follow-up	No = 0, Yes = 1
X3	Medication compliance	Good = 0, Poor = 1
X4	Compliance with wearing elastic stockings	Good = 0, Poor = 1
X5	D-D (mg/L)	< 0.84 = 0, ≥ 0.84 = 1
X6	FDP (mg/L)	< 4.53 = 0, ≥ 4.53 = 1

D-D: D-dimer; FDP: Fibrin degradation product.

Table 3 Multifactorial regression analysis affecting thrombotic recurrence in patients with lower-extremity deep venous thrombosis complicated with high-altitude polycythemia

Factor	β	SE	Wald χ2	OR	P value	95%CI
Age	0.783	0.245	10.214	2.188	0.001	1.354-3.537
Braking during follow-up	0.634	0.189	11.253	1.885	< 0.001	1.302-2.730
Medication compliance	0.893	0.232	14.816	2.442	< 0.001	1.550-3.849
Compliance with wearing elastic stockings	0.369	0.047	61.639	1.446	< 0.001	1.319-1.586
D-D	0.455	0.119	14.619	1.576	< 0.001	1.248-1.990
FDP	0.518	0.224	5.348	1.679	0.021	1.082-2.604

D-D: D-dimer; FDP: Fibrin degradation product.