Efficacy of acupoint injection in the treatment of chronic eczema and its influence on peripheral blood T cells

Table 1 General data analysis

Factors	Observation group (n = 40)	Control group (n = 40)	χ2/t/Z	P value
Sex			0.208	0.648
Male	25 (62.5)	23 (57.5)
Female	15 (37.5)	17 (42.5)
Age	58.68 ± 14.85	62.50 ± 17.11	-1.068	0.289
Course of disease	6.50 (5.00, 16.50)	6.00 (4.00, 12.00)	-0.560	0.575

Table 2 Comparison of effective rates, n (%)

Groups	n	Curative effect				Response rate	Marked response rate
		Non-response	Response	Marked response	Cure
Observation group	40	0 (0.0)	5 (12.5)	31 (77.5)	4 (10.0)	40 (100.0)	35 (87.5)
Control group	40	4 (10.0)	15 (37.5)	19 (47.5)	2 (5.0)	36 (90.0)	21 (52.5)
χ2							11.667
P value						0.1161	0.001

Table 3 Comparison of Eczema Area and Severity Index and Visual Analogue Scale scores (points)

Groups	n	EASI score				VAS score
		Before treatment	After treatment	t value	P value	Before treatment	After treatment	t value	P value
Observation group	40	7.52 ± 3.25	2.22 ± 1.30	12.002	0	6.05 ± 1.54	1.98 ± 1.07	21.747	0
Control group	40	7.30 ± 3.96	3.19 ± 2.52	9.058	0	6.08 ± 1.72	2.93 ± 1.27	12.498	0
t value		0.278	−2.17			−0.069	−3.615
P value		0.782	0.034			0.945	0.001

Table 4 Comparison of INF-γ, IL-2, IL-4, and IL-10 levels between the case and control groups

Parameters	Case group	Healthy control group	t value	P value
INF-γ	311.75 ± 136.86	399.17 ± 129.35	-2.582	0.011
IL-2	35.54 ± 19.11	57.25 ± 20.51	-4.479	0.000
IL-4	79.40 ± 9.62	60.72 ± 9.99	7.712	0.000
IL-10	66.00 ± 8.78	56.16 ± 6.90	4.659	0.000

Table 5 Comparison of INF-γ, IL-2, IL-4, and IL-10 levels between the observation and control groups before and after treatment

Parameters	Time point	Observation group	Control group	t value	P value
INF-γ	Before treatment	321.29 ± 135.22	302.21 ± 139.53	0.621	0.536
	After treatment	394.88 ± 115.70a	334.38 ± 137.47	2.13	0.036
IL-2	Before treatment	38.15 ± 19.98	32.93 ± 18.07	1.224	0.225
	After treatment	56.51 ± 18.00a	47.13 ± 20.04a	2.203	0.031
IL-4	Before treatment	81.01 ± 8.78	77.79 ± 10.25	1.508	0.136
	After treatment	61.31 ± 7.60a	67.20 ± 9.00a	−3.165	0.002
IL-10	Before treatment	65.94 ± 8.85	66.06 ± 8.83	−0.063	0.95
	After treatment	60.55 ± 11.86a	62.00 ± 8.84a	−0.623	0.535

^aP < 0.05 vs baseline.

Table 6 Adverse reaction and recurrence rates, n (%)

Groups	Adverse reactions	Recurrence
Observation group	1 (2.5)	3 (7.5)
Control group	0 (0.0)	7 (17.5)
χ2		1.829
P value	1.000	0.176