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Copyright ©The Author(s) 2023.
World J Clin Cases. Mar 16, 2023; 11(8): 1719-1729
Published online Mar 16, 2023. doi: 10.12998/wjcc.v11.i8.1719
Table 1 Studies in current literature regarding blepharoplasty
Ref.
Technique
Type of the study
Where (upper/lower eyelid)
Number of cases
Conclusions
Balzani et al[21], 2013LaserProspectiveUpper20Lift of 1.63 ± 0.68 mm of the upper eyelid at 6 mo
Bae-Harboe et al[16], 2014ReviewBoth/Fractional ablative CO2 laser is a valid solution to improve the appearance of periocular area
Toyos[20], 2017RetrospectiveUpper16Increase in the measurements for dermatochalasis and skin laxity at 6 mo follow-up and few side effects
Guida et al[23], 2018RetrospectiveBoth20Increase in the Global Assessment Improvement Scale; reduction of medium protrusions and depressions; improved texture at 2 mo also at 3D image reconstructions
Garcia et al[22], 2019Cohort, uncontrolledLower263Improvement in the eyelid area characterized by fewer rhytids and a younger appearance at 6 mo
Rossi et al[30], 2018Plasma exeresisProspective, controlled, evaluator-blindedBoth10Change in the conformation of the collagen fibers from huddled and coalesce presentation to long and straight fibers
Giroux et al[33], 2019Prospective, single centerUpper25About 2.5 mm of mean reduction at 12 mo follow-up
Theppornpitak et al[35], 2019Prospective, controlled, evaluator-blindedBoth18Effective and safe for treatment of mild-to-moderate periorbital wrinkles and darkening
Verner et al[32], 2020Prospective, single centerUpper17All patients had an improvement of dermathocalasis scale
Baroni[2], 2020Prospective, single centerUpper10General satisfaction for the patients (8 or more on VAS scale) and the absence of permanent side effects
Ziade and Desiree[29], 2020Case reportBoth2Safe and efficient non-surgical option. Few complications; hyperpigmentation is the most common, preventable whit small precautions
Ferreira et al[31], 2021ObservationalUpper16General post-treatment satisfaction (modified Q-bleph) and limited adverse events
Martín-Oviedo et al[38], 2013HARetrospectiveUpper26Effective in reducing paralytic lagophthalmos and controlling keratopathy in patients with temporary facial palsy
Romero et al[42], 2013RetrospectiveLower12Retraction was completely corrected in 96.3% of patients; improvement of the standardized MRD2 of 0.84 mm immediately after injection and 1.19 mm 9 mo later
Kohn et al[39], 2014Prospective, non-randomizedUpper8HA injection may be an effective and minimally invasive method to improve upper eyelid position for patients with mild eyelid retraction in both the active and inactive stages of TED
Romeo[12], 2016Cohort, prospectiveUpper154Upper eyelid area filling with HA was compared to surgical blepharoplasty as means of reaching eye rejuvenation. The study showed high patient satisfaction in regards of the aesthetic endpoint and long lasting results in a 12 mo period
Jiang et al[47], 2016Retrospective, single center clinical studyLower (tear-trough deformity)78Compared the use of HA to autologous fat injections. Fillers may be used alone in the treatment of TTD in patients with mild to moderate periorbital volume loss without severe orbital fat bulging
Romeo[46], 2019RetrospectiveUpper500Upper eyelid area filling with HA was compared to surgical blepharoplasty as means of reaching eye rejuvenation. The study showed high patient satisfaction in regards of the aesthetic endpoint and long lasting results in a 12 mo period
Xi et al[42], 2019RetrospectiveLower27Retraction was completely corrected in 96.3% of patients; improvement of the standardized MRD2 of 0.84 mm immediately after injection and 1.19 mm nine months later
Bladen and Malhotra[43], 2019Retrospective, single center case reviewUpper86 patients showed improvement; HA injection is considered a feasible option for treatment of epibleharon
Mani et al[49], 2013PMMARetrospective, single centerLower289Subdermal PMMA microspheres injection is a safe technique in the correction of infraorbital rhytids
Amore et al[50], 2019DeoxycholateMulti-center, observational prospectiveLower fat pads120Moderate to high patient satisfaction and therapeutic success in 85.83% of the patients enrolled
Lee et al[51], 2020Twisted polydioxanone threadsRetrospective, single centerLower40More than 77.5% of patients were satisfied with the outcome
Aust et al[52], 2018Platelet rich plasmaProspectiveLower20Statistically significant increase in skin firmness and skin elasticity, high level of patient satisfaction, and progressive improvement of the aesthetic outcome