Meng QZ, Wang Y, Li B, Xi Z, Wang M, Xiu JQ, Yang XP. Relationship between glycemic variability and cognitive function in lacune patients with type 2 diabetes. World J Clin Cases 2023; 11(5): 1019-1030 [PMID: 36874411 DOI: 10.12998/wjcc.v11.i5.1019]
Corresponding Author of This Article
Xiao-Peng Yang, Doctor, Chief Doctor, Department of Neurology, The Second Affiliated Hospital of Zhengzhou University, Jingba Road, Jinshui District, Zhengzhou 450003, Henan Province, China. yaxipe39@126.com
Research Domain of This Article
Clinical Neurology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Table 2 Comparison of blood glucose variability indicators in different cognitive function groups
Group
Number
SD
%CV
LAGE
TIR
Cognitive dysfunction
37
3.15 ± 0.53
31.28 ± 5.38
10.35 (6.51, 13.49)
47.04 (37.61, 53.52)
Normal cognitive function
107
2.84 ± 0.44
26.29 ± 4.83
10.01 (6.34, 12.27)
56.02 (45.78, 69.46)
Statistical parameters
-3.513
-5.254
-0.738
3.825
P value
< 0.001
< 0.001
0.461
< 0.001
Table 3 Multivariate logistic regression analysis of the influencing factors on infarct burden in patients with lacunes complicated with type 2 diabetes mellitus
β
SD
Wald
P value
OR
95%Cl
SD
1.269
0.526
2.412
0.016
3.558
[1.268, 9.978]
%CV
0.176
0.05
3.527
< 0.001
1.192
[1.081, 1.315]
TIR
-0.129
0.028
-4.648
< 0.001
0.874
[0.833, 0.928]
Table 4 Multivariate logistic regression analysis of the influencing factors on cognitive impairment in patients with lacunes complicated with type 2 diabetes mellitus
β
SD
Wald
P value
OR
95%CI
SD
0.919
0.465
1.976
0.048
2.506
[1.008, 6.230]
%CV
0.151
0.045
3.365
0.001
1.163
[1.065, 1.270]
TIR
-0.044
0.019
-2.253
0.024
0.957
[0.922, 0.994]
Citation: Meng QZ, Wang Y, Li B, Xi Z, Wang M, Xiu JQ, Yang XP. Relationship between glycemic variability and cognitive function in lacune patients with type 2 diabetes. World J Clin Cases 2023; 11(5): 1019-1030