Copyright
©The Author(s) 2023.
World J Clin Cases. Nov 26, 2023; 11(33): 8058-8064
Published online Nov 26, 2023. doi: 10.12998/wjcc.v11.i33.8058
Published online Nov 26, 2023. doi: 10.12998/wjcc.v11.i33.8058
Sex/age (yr) | ECOG | Disease involvement sites | Ann Arbor stage | IPI | Cell of origin | WBC (103/μL) | Hb (g/dL) | Plt | LDH (IU/L) | CRP (mg/dL) | Ferritin (ng/mL) |
F/67 | 4 | Right ethmoid sinus, liver, spleen, bilateral adrenal glands | IV | 5 | Non-GCB | 5.35 | 8.5 | 77 | 891 | 5.26 | 835 |
Tier 1 variants | Tier 2 variants | Tier 3 variants | |||||||||
Gene | DNA | Protein | VAF | Gene | DNA | Protein | VAF | Gene | DNA | Protein | VAF |
MYD88 | c.755T>C | p.Leu252Pro | 54.8% | PIM1 | c.237G>C | p.Glu79Asp | 30.77% | NOTCH1 | c.6283C>T | p.Arg2095Cys | 37.7% |
ETV6 | c.1123G>A | p.Gly375Arg | 14.4% | ||||||||
TET2 | c.3280A>T | p.Lys1094Ter | 16.0% | BTG2 | c.97C>T | p.Gln33Ter | 19.6% | HIST1H1E | c.367G>A | p.Ala123Thr | 15.6% |
TBL1XR1 | c.848G>A | p.Ser283Asn | 16.5% |
- Citation: Lee YP, Son SM, Kwon J. Asian variant intravascular large B-cell lymphoma with highly suspected central nervous system involvement: A case report. World J Clin Cases 2023; 11(33): 8058-8064
- URL: https://www.wjgnet.com/2307-8960/full/v11/i33/8058.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v11.i33.8058