Case Report
Copyright ©The Author(s) 2023.
World J Clin Cases. Nov 26, 2023; 11(33): 8058-8064
Published online Nov 26, 2023. doi: 10.12998/wjcc.v11.i33.8058
Table 1 Patient characteristics and laboratory findings at diagnosis
Sex/age (yr)
ECOG
Disease involvement sites
Ann Arbor stage
IPI
Cell of origin
WBC (103/μL)
Hb (g/dL)
Plt (103/μL)
LDH (IU/L)
CRP (mg/dL)
Ferritin (ng/mL)
F/674Right ethmoid sinus, liver, spleen, bilateral adrenal glandsIV5Non-GCB5.358.5778915.26835
Table 2 Variants found in next-generation sequencing
Tier 1 variantsTier 2 variantsTier 3 variants
Gene
DNA
Protein
VAF
Gene
DNA
Protein
VAF
Gene
DNA
Protein
VAF
MYD88c.755T>Cp.Leu252Pro54.8%PIM1c.237G>Cp.Glu79Asp30.77%NOTCH1c.6283C>Tp.Arg2095Cys37.7%
ETV6c.1123G>Ap.Gly375Arg14.4%
TET2c.3280A>Tp.Lys1094Ter16.0%BTG2c.97C>Tp.Gln33Ter19.6%HIST1H1Ec.367G>Ap.Ala123Thr15.6%
TBL1XR1c.848G>Ap.Ser283Asn16.5%