Observational Study
Copyright ©The Author(s) 2023.
World J Clin Cases. Nov 26, 2023; 11(33): 8013-8021
Published online Nov 26, 2023. doi: 10.12998/wjcc.v11.i33.8013
Table 1 Characteristics of the study group, n (%)
VariableSurgical site infection

P value
Absent (n = 315)
Present (n = 40)
Age (yr)65.3 ± 9. 666.4 ± 9.80.529
Male 227 (72.10)28 (70.00)0.785
BMI (kg/m2)22.68 ± 3.2225.12 ± 2.78< 0.001a
SFT (mm)14.20 (10.00–18.40)20.45 (17.00–26.63)< 0.001a
AD (mm)64.90 (50.60–78.20)82.50 (68.43–97.00)< 0.001a
Smoking 87 (27.60)15 (37.50)0.193
Alcohol use 66 (21.00)11 (27.50)0.344
Diabetes 40 (12.70)9 (22.50)0.090
Laparoscopic-assisted surgery96 (30.5)6 (15.00)0.042a
Hypertension95 (30.2)12 (30.0)0.984
Type of resection 0.371
Total gastrectomy206 (65.40)29 (34.60)
Partial gastrectomy109 (35.98)11 (27.50)
Operation time (min) 210.00 (180.00–240.00)240.00 (209.25–270.00)0.013a
Blood loss (mL)150.00 (100.00–200.00)150.00 (112.00–200.00)0.099
History of laparotomy47 (14.90)7 (17.50)0.669
Albumin (g/dL)39.37 ± 4.9940.29 ± 3.550.258
Prealbumin (g/dL)188.25 ± 59.06194.92 ± 63.090.509
TNM stage 0.304
I96 (29.2)10 (25.0)
II92 (30.5)17 (42.5)
III127 (40.3)13 (32.5)
Table 2 Risk factors for surgical site infection in univariate and multivariate analysis
VariableUnivariate analysis
P valueMultivariate analysis
P value
OR (95%CI)
OR (95%CI)
Age (yr)1.011 (0.977–1.047)0.528
Male0.905 (0.440–1.858)0.785
BMI (kg/m2)1.259 (1.133–1.398)< 0.001--
SFT (mm)1.137 (1.186–1.192)< 0.0011.150 (1.090–1.214) < 0.001a
AD (mm)1.031 (1.017–1.046)< 0.0011.024 (1.009–1.040) 0.002a
Smoking 1.572 (0.792–3.123)0.196
Alcohol use1.431 (0.679–3.015)0.346
Diabetes1.996 (0.885–4.500)0.096
Laparoscopic-assisted surgery0.403 (0.164–0.991)0.0480.286 (0.03–0.797) 0.017a
Hypertension0.992 (0.484–2.034)0.984
Type of resection
Total gastrectomy1.395 (0.671–2.900)0.373
Operation time (min)1.008 (1.002–1.015)0.0101.008 (1.001–1.015) 0.030a
Blood loss (mL)1.000 (0.999–1.002)0.659
History of laparotomy1.210 (0.505–2.894)0.669
Albumin (g/dL)1.041 (0.971–1.116)0.258
Prealbumin (g/dL)1.002 (0.996–1.001)0.508
TNM stage
I
II1.629 (0.709–3.743)0.250
III0.942 (0.396–2.241)0.892
Table 3 Diagnostic value of subcutaneous fat thickness, abdominal depth, and the product of subcutaneous fat thickness and abdominal depth for surgical site infection

Cutoff value
Sensitivity
Specificity
+LR
−LR
AUC
SFT16.550.8500.6572.4790.2280.770 (0.700–0.839)
AD67.850.8000.5781.8950.3460.715 (0.635–0.795)
SFT × AD11.110.8750.6352.3970.1970.810 (0.740–0.879)