Chen X, Dai L, Ma JZ, Chu XX, Dai L, Liu JM, Guo SW, Ru XW, Zhuang XS. Clinical study of NFNC in the treatment of acute exacerbation chronic obstructive pulmonary disease patients with respiratory failure. World J Clin Cases 2023; 11(32): 7770-7777 [PMID: 38073695 DOI: 10.12998/wjcc.v11.i32.7770]
Corresponding Author of This Article
Xue-Shi Zhuang, MM, Chief Physician, Department of Intensive Care Medicine, Lixin County People's Hospital, No. 17 Xiangyang Road, Lixin County, Bozhou 236700, Anhui Province, China. xshizhuang@163.com
Research Domain of This Article
Respiratory System
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
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Table 3 Comparison of blood gas analysis between the two groups of patients before and after treatment
Group
PaO2 (mmHg)
PaO2/FiO2 (mmHg)
PaCO2 (mmHg)
SaO2 (%)
Before treatment
After treatment
Before treatment
After treatment
Before treatment
After treatment
Before treatment
After treatment
Control group (40)
67.44 ± 7.23
93.27 ± 8.14
172.34 ± 11.25
291.81 ± 7.82
52.23 ± 6.57
39.67 ± 2.24
94.76 ± 3.15
96.45 ± 0.15
Therapy group (40)
67.40 ± 7.22
98.37 ± 8.20
172.31 ± 11.64
322.27 ± 7.81
52.24 ± 6.53
37.23 ± 2.26
94.75 ± 3.26
97.57 ± 0.16
t
0.025
2.792
0.012
17.431
0.007
4.850
0.014
32.298
P value
0.980
0.007
0.991
< 0.001
0.995
0.012
0.989
0.035
Table 4 Analysis of infection indicators in the two groups of patients
Group
White blood cell count (109/L)
C-reactive protein (g/L)
Calcitonin (g/L)
Before treatment
After treatment
Before treatment
After treatment
Before treatment
After treatment
Control group (40)
11.38 ± 1.10
10.41 ± 1.16
23.41 ± 2.27
8.71 ± 1.56
1.57 ± 0.33
3.41 ± 0.32
Therapy group (40)
11.40 ± 1.08
8.44 ± 1.65
23.43 ± 2.25
6.50 ± 1.82
1.55 ± 0.37
5.64 ± 1.15
t
0.082
6.177
0.040
5.831
0.255
11.815
P value
0.935
0.017
0.965
< 0.001
0.799
0.003
Citation: Chen X, Dai L, Ma JZ, Chu XX, Dai L, Liu JM, Guo SW, Ru XW, Zhuang XS. Clinical study of NFNC in the treatment of acute exacerbation chronic obstructive pulmonary disease patients with respiratory failure. World J Clin Cases 2023; 11(32): 7770-7777