Severe inflammatory disorder in trisomy 8 without myelodysplastic syndrome and response to methylprednisolone: A case report

Table 1 Timeline of the patient’s treatment

Date	Time	Event
5.24	15:00	Admission to hospital
	15:05	Intubation
	15:30	Anti-infection
	17:51	ICU admission
5.24-5.26	23:25-00:00	Vancomycin 1g q12h, imipenem 0.5g q6h and alveolar lavage fluid for mNGS
5.26		Second mNGS, blood culture and bone marrow puncture
5.29		Fluconazole 0.4 g qd
5.31		Methylprednisolone 500 mg qd
6.3		Methylprednisolone 250 mg qd and piperacillin-tazobactam 4.5 g q8h
6.5		Extubation
6.6		Methylprednisolone 120 mg qd
6.9		Methylprednisolone 60 mg qd
6.10		Transferred to department of respiratory medicine
6.15		Discharged

ICU: Intensive care unit; mNGS: Metagenomic next-generation sequencing.