Novel COL4A3 synonymous mutation causes Alport syndrome coexistent with immunoglobulin A nephropathy in a woman: A case report

Table 1 Proband’s laboratory tests

Biochemical items	Results
Urinary albumin	±
RBCs (/μL)	302.5
24 h urinary protein (mg)	223.2
ACR (mg/g)	181
Poikilocyte	75%
Total serum protein (g/L)	62.8
Albumin (g/L)	36.7
eGFR (mL/min per 1.73m2)	149.20
Serum creatinine (mg/dL)	0.52
Uric acid (mg/dL)	5.23
Potassium (mg/dL)	13.65
Total cholesterol (mg/dL)	257.16
Low density lipoprotein (mg/dL)	150.04
ANA	Negative
Anti-dsDNA antibody	Negative
IgA (g/L)	1.67
IgG (g/L)	11.30
IgM (g/L)	1.26
C3 (g/L)	1.03
C4 (g/L)	0.32
Anti-SSA antibody	Negative
Anti-SSB antibody	Negative
Hepatitis (A, B, or C) antibody	Negative

RBCs: Red blood cells; ACR: Albumin-creatinine ratio; eGFR: Estimated glomerular filtration rate; ANA: Anti-nuclear antibody; Anti-dsDNA: Anti-double-stranded DNA; C3: Complement 3; C4: Complement 4; Anti-SSA: Anti-Sjögren’s syndrome A; Anti-SSB: Anti-Sjögren’s syndrome B.