Acute hepatitis of unknown etiology in an adult female: A case report

Table 1 Trend of selected laboratory results

Blood test	Day of admission	Day 5	Day of discharge	Reference range
WBC × 109/L	6.3	4.5	4.7	4.5-11
Hgb (g/dL)	13.7	12.6	11.9	12-16
Platelets × 109/L	348	293	276	130-400
BUN (mg/dL)	9	8	7	9-23
sCr. (mg/dL)	0.87	0.72	0.68	0.55-1.02
Total bilirubin (mg/dL)	6.4	4	3.6	0.3-1.2
AST (U/L)	3159	> 1000	1775	8-34
ALT (U/L)	2500	2141	1903	10-49
Alkaline phosphatase (U/L)	714	563	486	46-116
INR	1.07	0.98	0.99	0.78-1.04

ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; BUN: Blood urea nitrogen; GFR: Glomerular filtration rate; HgB: Hemoglobin, sCr: Serum creatinine: WBC: White blood cell; INR: International normalized ratio.

Table 2 Serological and other pertinent laboratory results

		Reference range
Ceruloplasmin	62 mg/dL	18-53 mg/dL
Transferrin	362 mg/dL	188-341 mg/dL
Acetaminophen	< 2.0 mcg/mL	10-20 mcg/mL
HSV-1 IgM antibody	Negative	N/A
HSV- 2 IgM antibody	Negative	N/A
Mononucleosis screen	Negative	N/A
SMA titer screen	Negative	N/A
IgG	2225 mg/dL	600-1640 mg/dL
IgA	394 mg/dL	47-310 mg/dL
IgM	241 mg/dL	50-300 mg/dL
HBV surface antigen	Non-reactive	N/A
HBV core IgM	Non-reactive	N/A
HCV Antibody	Non-reactive	N/A
HCV RNA PCR quantitative	< 1.18 log IU/mL	N/A
HAV antibody IgM	Non-reactive	N/A
HEV antibody	Not detected	N/A
HIV 1/2	Non-reactive	N/A
EBV IgM titer	<36 U/mL, negative	< 36 U/mL, negative
LKM IgG antibody	Negative	< 20.0
Anti-mitochondrial antibody	Negative	Negative
SLA antibody	< 20.1	0.0-20.0
ANA screen IFA	Negative	N/A

N/A: Not applicable; HSV: Herpes simplex virus; HBV: Hepatitis B virus; HCV: Hepatitis C virus; HAV: Hepatitis A virus; HEV: Hepatits E virus; EBV: Ebstein Barr virus; SMA: Smooth muscle antibody; LKM: Liver kidney microsome; SLA: Soluble liver antigen.