High expression of autophagy-related gene EIF4EBP1 could promote tamoxifen resistance and predict poor prognosis in breast cancer

Table 1 Relationships between the expression of eukaryotic translation initiation factor 4E binding protein 1 and the clinical-pathological features in breast cancer tissues

Groups	n	Expression of EIF4EBP1		P value
		Low expression	High expression
Age in yr				0.5273
< 50	34	20	14
≥ 50	37	19	18
Metastasis of lymph nodes				0.0000
Negative	23	20	3
1 ≤ N+ ≤ 3	20	12	8
N+ > 3	28	7	21
Radiotherapy				0.7274
No	36	20	16
Yes	35	18	17
Chemotherapy				0.0005
TAM	52	35	17
TAM + OFS	19	4	15
Tumor stage				0.8371
I	17	9	8
II	44	24	20
III	9	5	4
IV	1	1	0
Histological grade				0.3111
I-II	59	34	25
III	12	5	7
Metastasis stage				0.0000
M0	48	35	13
M1	23	4	19

EIF4EBP1: Eukaryotic translation initiation factor 4E binding protein 1; OFS: Ovarian function suppression; TAM: Tamoxifen.