Neurofibromatosis type 1 with multiple gastrointestinal stromal tumors: A case report

Table 1 Comparison of neurofibromatosis 1-associated and sporadic gastrointestinal intestinal stromal tumor

	NF1 with GIST	Sporadic GIST
Age of onset	Young	Older
Most common sites	Small intestine (90%)	Stomach (60%-70%)
Number of tumors	Often multiple	Often solitary
Nuclear fission rate	Low	High
KIT and PDGFRA gene mutation	Rare	Common
Imatinib treatment	Ineffective	Effective
Disease progression	Slow	Quick
Postoperative recurrence rate	Low	High
Prognosis	Good	Common

NF1: Neurofibromatosis 1; GIST: Gastrointestinal stromal tumor.