T1 rectal mucinous adenocarcinoma with bilateral enlarged lateral lymph nodes and unilateral metastasis: A case report

Table 1 The detailed information of the previous five cases and our case

	Case 1	Case 2	Case 3	Case 4	Case 5	Case 6
Ref.	Hara et al[6], 2008	Sueda et al[7], 2013	Ogawa et al[8], 2016	Tanishima et al[9], 2017	Zhang et al[10], 2020	Ours, 2022
Sex	Male	Female	Female	Male	Male	Female
Age (yr)	61	41	35	56	45	36
Risk factors of LNM
Depth of invasion (μm)	-	-	3000	Head invasion	-	-
Histological type	Well	Moderately	Moderately	Moderately	Well	Moderately
Budding	-	-	-	1	-	-
Time after 1st surgery (mo)	22	6	Simultaneous	6	Simultaneous	Simultaneous
Treatment	Extended, LLND	Extended, LLND	TME + LLND	LLND	TME + LLND	TME + LLND
Bilateral or unilateral LLND	Unilateral	Unilateral	Unilateral	Unilateral	Unilateral	Bilateral
Isolated or multiple LLNM	Isolated	Isolated	Isolated	Multiple	Isolated	Multiple
Adjuvant therapy after LLND	None	None	Tegafururacil + leucovorin	FOLFOX	XELOX + radiotherapy	XELOX + radiotherapy
Follow-up period (mo)	44	12	48	30	10	12
Prognosis	Alive	Alive	Alive	Alive	Alive	Alive

LNM: Lymph node metastasis; TME: Total mesorectal excision; LLND: Lateral lymph node dissection; LLNM: Lateral lymph node metastasis; FOLFOX: Fluorouracil, leucovorin, and oxaliplatin; XELOX: Oxaliplatin plus capecitabine.