Case Report
Copyright ©The Author(s) 2022.
World J Clin Cases. Oct 6, 2022; 10(28): 10227-10235
Published online Oct 6, 2022. doi: 10.12998/wjcc.v10.i28.10227
Table 1 Cases of peripheral nerve compression due to myeloid sarcoma over the last 10 years
Ref.
Gender/age (yr)
Leukaemia-Yes (type)/No
Symptoms
Involved segment
Lesion invasion site
Imaging
Bone marrow biopsy
Laboratory test findings
Treatment regimens
Pathology and immunohistochemistry examination
McCarty et al[35]M/14NoHeadaches, urinary incontinenceIntracranial, extracranial, sacral spineCerebral nerve, sacral nerve rootMRIPositiveWBC: 51 × 109/L; HGB: 113 g/L; platelets: 130 × 109/LRadiotherapy, chemotherapy-
Zhu et al[36]M/36NoAbdominal pain, pain in right eye, eye protrusion with inability to closePancreas, right eyePancreas, right optic nerveCT, MRI, PET-CTNegativeMildly elevated liver and pancreatic enzymesRadiotherapy, chemotherapyKi-67 (+ 80%), P53 (approximately 50%), CD43 (+), MPO (+)
Bai et al[24]M/29NoSevere radiating pain in lower limbs, moderate difficulty in urinationWaistLumbar spine attachment, spinal cordCT, MRI, SPECTNegativeWBC: 6.01 × 109/L; RBC: 5.00 × 1012/L; HGB: 158 g/L; platelets: 236 × 109/L; CRP: 2 mg/L; rrythrocyte sedimentation rate (ESR): 4 mm/1 h; procalcitonin (PCT): 0.27 ng/mLLesion excision, chemotherapyCD33 (+), MPO (+)
Valsamis et al[37]M/56NoPain in right hip radiating down right legRight hipRight sciatic nerve, lumbosacral plexusUltrasound, MRI-MONO: 0.9 × 109/L; RBC: 3.56 × 1012/L; HGB: 116 g/L; mean cell volume: 102 fL; CRP: 13 mg/L--
Pandey et al[38](1) F/44; (2) F/16; (3) F/63; (4) M/53(1,2,4) No; (3) Yes (AML)(1) Neck pain, right arm weakness, and muscle wasting; (2) back pain, bilateral lower extremity tingling, and weakness; (3) lower back pain, bilateral lower extremity weakness, and bowel incontinence; and (4) lower back pain, hip pain, lower extremity weakness, and muscle pain(1) Cervical spine; (2) thoracic spine; (3) thoracic spine; and (4) lumbar spineSpinal cord compression-(1) Negative; (2) positive; (3) negative; and (4) positive(1) and (3) Negative; (2) and (4) high WBCLesion excision-
Snoj et al[39]F/49Yes [MDS (refractory anaemia with excess blasts)]Weakness and decreased sensation in right arm, right supraclavicular massLeft upper limbLeft brachial plexusUltrasound, MRI--Radiotherapy, chemotherapy-
Yamamoto et al[40]F/34Yes (Chronic phase chronic myeloid leukaemia)Pain in left eye, protrusion of eyeball, blurred vision with headache, and vomitingLeft eyeLeft optic nerveMRI---CD13 (+), CD33 (+), CD117 (+)
Koh et al[41]M/68Yes (chronic myeloid leukemia)Low back pain and numbness in both legs with radiating painThoracic and sacral spineSpinal cordMRI, CT--Chemotherapy-
Kim et al[42]M/62Yes (acute myeloid leukaemia, M2)Abnormal sensation and weakness of ankle flexion in posterior aspect of left calf and footLower left limbSciatic nerveUltrasound, MRI---MPO (+)
Rambeloson et al[43]M/1NoBilateral ophthalmoplegia with loss of visionBilateral eyeOcculomotor nerveMyelogram, CT----
Slouma et al[31]M/56NoProgressive back pain and bilateral sciaticaWaistLumbar 5th nerve rootMRI-WBC: 83 × 109/L; absolute neutrophil count: 60 × 109/LChemotherapyMPO (+), CD13 (+), CD33 (+), CD14 (+), CD4 (+), CD46 (+)
Anqi et al[44]M/24NoLimp, numbness in right lower limb, mild urinary frequency, urinary and faecal incontinenceLumbosacral regionLumbar and sacral spineMRI-NormalLesion excision, chemotherapyMPO, CD34, CD43 (+)
Ha et al[34]F/38Yes (AML)Subacute radiating pain in right upper limb, weaknessRight upper limbRight brachial plexusMRI, PET/CT--Chemotherapy, hormone shock therapyCD13(+), CD14 (+) ,CD15 (+), CD33 (+), CD54 (+), CD64 (+), CD117 (+) , MPO (+)