Shi QQ, Huang GX, Li W, Yang JR, Ning XY. Rectal nonsteroidal anti-inflammatory drugs, glyceryl trinitrate, or combinations for prophylaxis of post-endoscopic retrograde cholangiopancreatography pancreatitis: A network meta-analysis. World J Clin Cases 2022; 10(22): 7859-7871 [PMID: 36158503 DOI: 10.12998/wjcc.v10.i22.7859]
Corresponding Author of This Article
Jian-Rong Yang, MD, MMed, Chief Physician, Department of Hepatobiliary, Pancreas and Spleen Surgery, the People's Hospital of Guangxi Zhuang Autonomous Region, No.6 Taoyuan Road, Qingxiu District, Nanning City 530021, Guangxi Zhuang Autonomous Region, China. 1637340358@qq.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Meta-Analysis
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Table 3 League table with OR estimates of each pair of interventions accompanied by 95%CI according to the prevention of total PEP (significant difference when OR < 1 and CI < 1)
Indomethacin+GTN
Diclofenac 100 mg
sub-GTN
Indomethacin
Diclofenac 50 mg
tra-GTN
Naproxen
Pla
0.62 (0.21, 1.82)
0.61 (0.16, 2.38)
0.99 (0.29, 3.37)
0.42 (0.18, 1.02)
0.69 (0.33, 1.43)
0.69 (0.23, 2.10)
0.30 (0.07, 1.30)
0.49 (0.13, 1.86)
0.50 (0.11, 2.34)
0.72 (0.21, 2.42)
0.30 (0.10, 0.89)
0.49 (0.20, 1.22)
0.49 (0.15, 1.66)
0.71 (0.33, 1.50)
0.99 (0.26, 3.68)
0.26 (0.08, 0.86)
0.43 (0.17, 1.10)
0.43 (0.11, 1.62)
0.62 (0.26, 1.47)
0.86 (0.21, 3.58)
0.87 (0.30, 2.50)
0.21 (0.09, 0.50)
0.34 (0.18, 0.65)
0.34 (0.12, 0.97)
0.49 (0.33, 0.73)
0.69 (0.22, 2.18)
0.70 (0.37, 1.32)
0.80 (0.35, 1.83)
Table 4 League table with OR estimates of each pair of interventions accompanied by 95%CI according to the prevention of mild PEP (significant difference when OR < 1 and CI < 1)
Indomethacin+GTN
Diclofenac 100 mg
Indomethacin
tra-GTN
Naproxen
Diclofenac 50 mg
Placebo
0.59 (0.19, 1.86)
0.46 (0.19, 1.12)
0.77 (0.35, 1.72)
0.38 (0.12, 1.20)
0.65 (0.24, 1.75)
0.84 (0.38, 1.85)
0.38 (0.11, 1.35)
0.64 (0.22, 1.87)
0.83 (0.32, 2.14)
0.99 (0.31, 3.14)
0.32 (0.08, 1.39)
0.54 (0.14, 2.11)
0.70 (0.21, 2.37)
0.84 (0.22, 3.19)
0.85 (0.19, 3.71)
0.27 (0.11, 0.67)
0.46 (0.23, 0.94)
0.59 (0.40, 0.88)
0.71 (0.36, 1.41)
0.72 (0.29, 1.78)
0.84 (0.27, 2.66)
Table 5 League table with OR estimates of each pair of interventions accompanied by 95%CI according to the prevention of moderate-to-severe PEP (significant difference when OR < 1 and CI < 1)
Indomethacin+GTN
Diclofenac 100 mg
Indomethacin
Diclofenac 50 mg
tra-GTN
Naproxen
Placebo
0.71 (0.17, 2.96)
0.44 (0.17, 1.16)
0.61 (0.20, 1.87)
0.47 (0.05, 4.40)
0.66 (0.07, 6.62)
1.07 (0.13, 8.55)
0.28 (0.09, 0.85)
0.39 (0.11, 1.36)
0.63 (0.30, 1.34)
0.59 (0.07, 4.95)
0.24 (0.07, 0.82)
0.34 (0.11, 1.02)
0.55 (0.24, 1.27)
0.52 (0.06, 4.65)
0.88 (0.32, 2.46)
0.19 (0.08, 0.48)
0.27 (0.09, 0.79)
0.43 (0.28, 0.66)
0.41 (0.05, 3.11)
0.69 (0.37, 1.28)
0.78 (0.35, 1.77)
Citation: Shi QQ, Huang GX, Li W, Yang JR, Ning XY. Rectal nonsteroidal anti-inflammatory drugs, glyceryl trinitrate, or combinations for prophylaxis of post-endoscopic retrograde cholangiopancreatography pancreatitis: A network meta-analysis. World J Clin Cases 2022; 10(22): 7859-7871