Tang CY, Wen F. Serum ferritin levels in children with attention deficit hyperactivity disorder and tic disorder. World J Clin Cases 2022; 10(22): 7749-7759 [PMID: 36158507 DOI: 10.12998/wjcc.v10.i22.7749]
Corresponding Author of This Article
Fang Wen, MM, Chief Doctor, Department of Psychiatry, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, No. 56 Nanlishi Road, Beijing 100045, China. wenfang0812@163.com
Research Domain of This Article
Psychiatry
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Table 2 Description of the average distribution of age and serum ferritin level
Grouping
Mini
Max
Mean
SD
Skewness
Kurtosis
95%CI lower
95%CI upper
HC age
5.00
12.00
8.57
2.28
-0.03
-1.26
8.47
8.67
HC SF
1.30
200.00
71.66
51.99
0.76
-0.51
69.38
50.63
ADHD age
5.00
12.00
7.92
1.85
0.47
-0.65
7.83
8.01
ADHD SF
2.60
148.60
36.63
20.32
1.53
3.42
35.62
37.64
TD age
5.00
12.00
7.61
2.03
0.49
-0.76
7.52
7.71
TD SF
2.90
262.70
35.43
20.64
2.66
15.31
34.45
36.41
ASD age
1
14.00
6.14
2.88
0.47
0.35
5.55
6.73
ASD SF
4.7
89.6
30.98
18.11
1.25
1.41
27.26
34.71
Table 3 The β of attention deficit hyperactivity disorder/tic disorder for the level of serum ferritin among children
Model 1
Model 2
Model 3
β
P
β
P
β
P
Among children with ADHD
ADHD
-0.107
< 0.001
-0.107
< 0.001
-0.110
< 0.001
Age
0.011
< 0.001
0.011
< 0.001
Sex
0.021
< 0.001
Among children with TD
TD
-0.113
< 0.001
-0.108
< 0.001
-0.114
< 0.001
Age
0.001
< 0.001
0.010
< 0.001
Sex
0.021
< 0.001
Table 4 Odds ratio of attention deficit hyperactivity disorder/tic disorder for low serum ferritin among children
Model 1, OR (95%CI)
Model 2, OR (95%CI)
Model 3, OR (95%CI)
Among children with ADHD
ADHD
0.94 (0.74-1.19)
0.90 (0.71-1.15)
0.82 (0.63-1.06)
Age
0.68 (0.46-1.01)
0.68 (0.46-1.01)
Sex
1.22 (0.94-1.58)
Among children with TD
TD
0.97 (0.77-1.22)
0.91 (0.72-1.15)
0.99 (0.78-1.28)
Age
0.65 (0.93-1.56)
0.65 (0.95-1.53)
Sex
1.38 (1.08-1.75)
Table 5 Comparison of serum ferritin in different age groups
Age (yr)
HC
ADHD
TD
5
63.15 ± 52.54
28.77 ± 17.54
29.73 ± 21.55
6
65.05 ± 48.64
31.66 ± 16.38
32.68 ± 16.54
7
75.24 ± 55.18
33.78 ± 19.16
33.99 ± 19.48
8
79.05 ± 53.37
37.93 ± 20.34
36.63 ± 16.76
9
77.88 ± 52.77
43.27 ± 22.41
41.92 ± 23.44
10
77.10 ± 49.96
43.59 ± 21.15
40.74 ± 18.28
11
68.65 ± 49.32
42.36 ± 24.06
38.17 ± 25.55
12
66.85 ± 52.22
32.66 ± 18.77
39.16 ± 28.08
F
3.651
14.206
9.381
P
0.001
0.000
0.000
Citation: Tang CY, Wen F. Serum ferritin levels in children with attention deficit hyperactivity disorder and tic disorder. World J Clin Cases 2022; 10(22): 7749-7759