Shi MK, Mei YQ, Shi JL. Short- (30-90 days) and mid-term (1-3 years) outcomes and prognostic factors of patients with esophageal cancer undergoing surgical treatments. World J Clin Cases 2022; 10(22): 7708-7719 [PMID: 36158480 DOI: 10.12998/wjcc.v10.i22.7708]
Corresponding Author of This Article
Jia-Lun Shi, MS, Doctor, Department of Cardiothoracic Surgery, Heping Hospital Affiliated to Changzhi Medical College, Department of Cardiothoracic Surgery, Heping Hospital Affiliated to Changzhi Medical College, Changzhi 046000, Shanxi Province, China. hepingdoctor@126.com
Research Domain of This Article
Oncology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
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Table 4 Univariable and multivariable Cox regression analyses of overall survival
Univariable
Multivariable
HR
95%CI
P
HR
95%CI
P
Age
1.018
0.979, 1.059
0.377
Sex
Female
ref
Male
1.020
0.58, 1.796
0.945
Body mass index
< 28
ref
≥ 28
1.912
0.816, 4.478
0.136
Smoking
1.185
0.663, 2.118
0.567
Drinking
0.916
0.285, 2.942
0.882
Family history of esophagus cancer
1.372
0.545, 3.452
0.501
Hypertension
0.939
0.530, 1.663
0.829
Diabetes
1.898
0.810, 4.449
0.140
Hemoglobin
0.987
0.971, 1.004
0.125
D-dimer
1.000
0.999, 1.001
0.782
Albumin
1.004
0.945, 1.067
0.897
Creatinine
1.020
1.003, 1.036
0.020
1.016
1, 1.032
0.050
Tumor diameter
1.244
1.083, 1.429
0.002
T stage
Tis/0-2
ref
ref
3-4
2.327
1.331, 4.068
0.003
1.869
0.98, 3.564
0.058
N stage
0
ref
1-3
2.869
1.659, 4.962
< 0.001
G stage
< 2
ref
≥ 2
1.990
1.062, 3.73
0.032
pTNM stage
0/I/II
ref
ref
III/IVA
4.117
2.349, 7.213
< 0.001
4.189
2.190, 8.012
< 0.001
Pathological type
Squamous cell carcinoma
ref
Others
0.616
0.222, 1.711
0.353
Received preoperative radiotherapy or chemotherapy
1.157
0.592, 2.261
0.669
Operation method
ESD/endoscopy/thoracoscopy/laparoscopy
ref
Thoracotomy/laparotomy
0.867
0.312, 2.405
0.784
Lymph node dissection
3.622
0.500, 26.255
0.203
Postoperative radiotherapy and/ or chemotherapy
0.449
0.225, 0.897
0.023
0.234
0.112, 0.488
< 0.001
Number of metastatic lymph nodes
1.277
1.109, 1.471
0.001
CCI
1.029
1.014, 1.044
< 0.001
1.018
1.004, 1.032
0.011
Citation: Shi MK, Mei YQ, Shi JL. Short- (30-90 days) and mid-term (1-3 years) outcomes and prognostic factors of patients with esophageal cancer undergoing surgical treatments. World J Clin Cases 2022; 10(22): 7708-7719