PD-1 inhibitor in combination with fruquintinib therapy for initial unresectable colorectal cancer: A case report

Table 1 Organization of the case into a timeline

Date	[T]/[S]/[E]
May, 2021	[E] Colonoscopy, pathological examination, Abdominal CT examination
June, 2021	[E] The evaluation of three tumour markers in the serum (AFP, CEA, CA199), Faecal occult blood test; [T] Four cycles of immunotherapy (paprizumab+ fruquintinib)
July, 2021	[E] Abdominal CT examination
September, 2021	[E] Abdominal CT examination
October, 2021	[T] Radical resection of the right colon cancer; [E] Pathologic evaluation of the posttreatment tumour regression after neoadjuvant therapy; [S] The patient’s general appearance had improved; the patient was discharged smoothly
November, 2021	[E] An abdominal CT was re-evaluated after surgery

[T]: Treatment; [S]: Symptoms; [E]: Examination; CT: Computed tomography.