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World J Clin Cases. Aug 16, 2013; 1(5): 169-171
Published online Aug 16, 2013. doi: 10.12998/wjcc.v1.i5.169
Published online Aug 16, 2013. doi: 10.12998/wjcc.v1.i5.169
Reference | Study design | Results |
Deeg et al[7] | Case report, patient with type 2 DM | Repeated episodes of hypoglycemia in a patient treated with glyburide. Fasting hypoglycemia (with hyperinsulinemia) continued 2 wk after glyburide was suspended and while receiving fluoxetine |
Khoza et al[8] | Case reports, review of published reports | 17 patients with glucose dysregulation (9 hyperglycemia; 8 hypoglycemia, one of them with fluoxetine) after initiation of treatment with antidepressant agents The authors concluded it was not clear whether changes in glucose regulation were due to antidepressants or to changes in mood and lifestyle |
Sawka et al[9] | Case report, patient with type 1 DM | Reduced insulin requirements and hypoglycemia unawareness during treatment with fluoxetine |
Maheux et al[10] | Experimental design, obese subjects with type 2 DM | Fluoxetine improved insulin sensitivity in a clamp study, independent of weight loss |
Potter van Loon et al[11] | Experimental design, obese subjects with and without type 2 DM | Fluoxetine improved hepatic and peripheral insulin sensitivity in a clamp study |
Lear et al[12] | Case report, patient with type 1 DM | Fluoxetine side effects mimicked hypoglycaemia |
Fernández López et al[13] | Case report, non-diabetic woman | Clinical presentation with symptoms of hypoglycemia but without analytical confirmation |
Briscoe et al[14] | Experimental design, patients with type 1 DM | 6-wk administration of fluoxetine amplified autonomic nervous system and metabolic counter-regulatory mechanisms during moderate hypoglycemia. |
Erenmemisoglu et al[15] | Experimental design, healthy and alloxan-induced diabetic mice | Fluoxetine and sertraline did not modify insulin concentrations but reduced plasma glucose |
Gomez et al[16] | Experimental design, diabetic and non-diabetic rats | Sertraline prevented the increase in glycemia induced by an oral glucose load while fluoxetine had the opposite effect |
Kesim et al[17] | Experimental design, healthy and diabetic mice | Paroxetine and fluoxetine had no significant or controversial effects on glycemia |
- Citation: Biagetti B, Corcoy R. Hypoglycemia associated with fluoxetine treatment in a patient with type 1 diabetes. World J Clin Cases 2013; 1(5): 169-171
- URL: https://www.wjgnet.com/2307-8960/full/v1/i5/169.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v1.i5.169