Published online Jul 26, 2023. doi: 10.12998/wjcc.v11.i21.5056
Peer-review started: May 9, 2023
First decision: May 25, 2023
Revised: June 5, 2023
Accepted: July 3, 2023
Article in press: July 3, 2023
Published online: July 26, 2023
Processing time: 78 Days and 21.5 Hours
Gastroparesis is a common digestive disorder characterized by delayed gastric emptying, which can lead to symptoms such as nausea, vomiting, abdominal pain, and poor appetite. Traditional Chinese medicine (TCM) has been used for centuries to treat gastrointestinal disorders, including gastroparesis. TCM theory suggests that spleen and stomach qi deficiency syndrome is one of the main pathogenic factors in gastroparesis. Nursing care plays an important role in the treatment of gastroparesis, and TCM nursing interventions have shown promi
To analyze the clinical effect of traditional Chinese medicine nursing intervention in the treatment of gastric paraplegia with spleen stomach deficiency syndrome.
From January 2020 to July 2021, 80 patients with gastroparesis of spleen stomach qi deficiency type diagnosed in our hospital were selected for the study. The 80 patients were randomly divided into a control group and an experimental group, with 40 cases in each group. During the treatment period, the control group received routine nursing interventions, while the experimental group received traditional Chinese medicine nursing procedures. Compare the nursing effects of the two groups and observe the changes in traditional Chinese medicine symptom scores, pain levels, and sleep quality before and after treatment.
After treatment, comparing the treatment effects of the two groups, the total effective rate of the experimental group was significantly higher than that of the control group, with statistical significance (P < 0.05). There was no statistically significant difference in the TCM symptom score, visual analogue scale (VAS) score, and Pittsburgh sleep quality index (PSQI) score between the two groups before treatment (P > 0.05). However, after treatment, the TCM syndrome scores, VAS scores, and PSQI scores of the experimental group were significantly lower than those of the control group, with a statistically significant difference (P < 0.05).
In the clinical nursing intervention of patients with mild gastroparesis due to spleen and stomach qi deficiency, the traditional Chinese medicine nursing plan has good clinical application value and nursing effect, and has a good effect on improving patients’ pain and sleep quality.
Core Tip: Traditional Chinese medicine is a traditional Chinese medicine that refers to stomach pain as gastroparesis, which is mainly caused by cold, heat, qi stagnation, blood stasis, and food accumulation. This study shows that traditional Chinese nursing helps relieve gastroparesis symptoms and improve patients’ quality of life.
- Citation: Yu YH, Yu YS, Cheng XH. Clinical effects of a traditional Chinese medicine nursing programme to intervene in gastric pain of the spleen and stomach with Qi deficiency. World J Clin Cases 2023; 11(21): 5056-5062
- URL: https://www.wjgnet.com/2307-8960/full/v11/i21/5056.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v11.i21.5056
Traditional Chinese medicine is a traditional Chinese medicine that refers to stomach pain as gastroparesis, which is mainly caused by cold, heat, qi stagnation, blood stasis, and food accumulation. In addition, there are emotional disorders that can cause stomach pain[1]. Gastric paresis is divided into eight symptoms in traditional Chinese medicine, and deficiency of spleen and stomach qi is one of the most common symptoms. Repeated attacks can have a significant impact on the daily life of patients. The main principle of clinical treatment of gastroparesis in traditional Chinese medicine is to coordinate with the stomach to relieve pain, warm the stomach and strengthen the spleen, which can improve the clinical symptoms of patients. However, some studies[2] point out that only traditional Chinese medicine treatment has limited efficacy, and traditional Chinese medicine nursing intervention can further improve the efficacy and promote rehabilitation. This article selects 80 patients with gastric paresis of spleen and stomach qi deficiency type diagnosed in our hospital from January 2020 to July 2021 for research. The research report is as follows.
With the approval of the ethics committee of our hospital, 80 patients with gastric paresis due to deficiency of spleen and stomach qi diagnosed in our hospital from January 2020 to July 2021 were selected for study. Eighty patients were randomly divided into control group and experimental group. There were 40 patients with gastroparesis in the control group, with a male to female ratio of 23:17; The age range is 20-66 years, with a median of (41.55 ± 5.87) years; The course of disease ranged from 0.5 to 1.0 year, with an average of (0.89 ± 0.24) years. There were 40 patients with gastroparesis in the experimental group, with a male to female ratio of 25:15; The age range is 22-65 years, with a median of (41.51 ± 5.89) years; The course of disease ranged from 0.5 to 1.5 years, with an average of (0.93 ± 0.22) years. When comparing the above general information of the two groups of patients with gastroparesis due to deficiency of spleen and stomach qi, there was no statistically significant difference (P > 0.05). Inclusion criteria: (1) Patients who meet the relevant diagnostic criteria for gastroparesis due to deficiency of spleen and stomach qi[3]; (2) a person with normal communication and thinking skills; and (3) sign an informed consent form. Exclusion criteria: (1) Patients with cardiopulmonary insufficiency; (2) patients with other digestive system diseases; (3) pregnancy or lactation; and (4) patients with neurological disorders.
After admission, both groups were treated with Chinese herbal medicines to warm the spleen, harmonize the stomach and relieve pain. During the treatment period, the control group was cared for with conventional nursing interventions, including observation of the condition, dietary guidance, and medication guidance. For patients with symptoms such as cold extremities and paroxysmal pain, moxibustion can be applied to acupuncture points such as the foot Sanli point, Shen Que point and Stomach Yu point, while keeping the patient warm and instructing him to use Chinese herbs to the patient’s feet can be soaked to stimulate the acupuncture points on the feet to improve clinical symptoms. Application of appropriate Chinese medicine techniques: Nursing staff need to reasonably apply various appropriate Chinese medicine techniques according to the patient’s specific condition, such as auricular point embedding, acupressure, acupressure and moxibustion, etc. At the same time, during the application of appropriate Chinese medicine techniques, the patient needs to be closely observed, and once the patient is found to have uncomfortable symptoms, he needs to stop immediately and promptly cooperate with the doctor for symptomatic treatment. Dietary adjustment: The nursing staff can make a reasonable dietary plan for the patient according to the results of the patient’s specific identification and dietary preferences, such as increasing the intake of foods such as yam, japonica rice and red dates in the daily diet, while avoiding foods such as mung beans, bitter gourd and bananas, which can easily damage the temper. In addition, the patient is advised to eat slowly and chew carefully, and to eat regularly in order to minimise stomach irritation. Emo
Observe the effect of care for patients in both groups. If the patients’ TCM symptom scores decreased by more than 80% after care compared with those before care, it was said to be effective; if the patients’ TCM symptom scores decreased between 60% and 80% after care compared with those before care, it was said to be ineffective; if the above criteria were not met, it was said to be ineffective[4]. Total effective rate = (effective + effective)/total number of cases × 100%. To observe the changes in TCM symptom scores, pain level and sleep quality of the two groups before and after care. The TCM symptom scores were mainly assessed in terms of gastroparesis, gastric distension and fatigue, and were recorded as 0 (no symptoms), 3 (mild symptoms), 6 (moderate symptoms), and 9 (severe symptoms) respectively according to the severity of symptoms. The pain scale is the visual analogue scale (VAS) with a total score of 0-10, and the sleep quality scale is the Pittsburgh sleep quality index (PSQI) with a total score of 0-21, with the lower score being preferred[5].
The study data were analysed by the statistical software SPSS22.0. The measurement data were expressed as (mean ± SD) by t-test and the count data were expressed as n (%) by χ2 test. P < 0.05 was considered a statistically significant difference.
As shown in Table 1, after the care, the comparison of the nursing effect between groups, the total effective rate of the experimental group was significantly higher than that of the control group, and the difference was statistically significant (P < 0.05).
Grouping | Number of examples | Visible effect | Effective | Invalid | Total efficiency |
Control group | 40 | 15 (37.50) | 15 (37.50) | 10 (25.00) | 30 (75.00) |
Experimental group | 40 | 27 (67.50) | 10 (25.00) | 3 (7.50) | 37 (92.50) |
χ2 | - | - | - | - | 4.501 |
P | - | - | - | - | 0.034 |
As shown in Table 2, the differences in TCM symptom scores, VAS scores and PSQI scores between groups before care were not statistically significant (P > 0.05), and after care, the experimental group had significantly lower TCM symptom scores, VAS scores and PSQI scores than the control group, and the differences were all statistically significant (P < 0.05).
Grouping | Number of examples | Chinese Medicine symptom score | VAS score | PSQI score | |||
Before care | After care | Before care | After care | Before care | After care | ||
Control group | 40 | 19.82 ± 4.04 | 14.27 ± 2.67 | 6.81 ± 1.34 | 4.02 ± 1.20 | 17.15 ± 1.09 | 13.04 ± 1.10 |
Experimental group | 40 | 19.88 ± 4.01 | 12.05 ± 2.25 | 6.77 ± 1.35 | 3.11 ± 1.18 | 17.09 ± 1.10 | 10.82 ± 1.07 |
t | - | 0.067 | 4.021 | 0.133 | 3.420 | 0.245 | 9.149 |
P | - | 0.947 | 0.000 | 0.894 | 0.001 | 0.807 | 0.000 |
In recent years, as people’s dietary habits change, the incidence of digestive disorders is on the rise. Gastroparesis, as one of the common clinical disorders, refers to stomach pain and gas pain in Chinese medicine and peptic ulcer and chronic gastritis in Western medicine. It is a common form of gastroparesis with symptoms such as vague pain in the stomach and stomach, pale tongue and slow pulse, and poor appetite, and is prone to recurrent attacks, with long treatment cycles and serious impact on patients’ daily lives. For patients with gastroparesis, pharmacological treatment is the most common treatment method, which has proven to be effective. However, some studies have pointed out that the long treatment time of patients may affect their compliance and psychological status, so it is necessary to strengthen the nursing intervention during treatment.
In a randomized controlled nursing study of 120 patients with stomachache due to deficiency of spleen and stomach qi, some studies[6-17] pointed out that traditional Chinese medicine nursing intervention can alleviate the pain symptoms of patients to a greater extent in terms of symptom care, dietary care, and emotional and spiritual guidance, and its nursing effect is significantly superior to conventional nursing. After nursing, the total effective rate of the experimental group was significantly higher than that of the control group, with a statistically significant difference (P < 0.05). The difference was statistically significant (P < 0.05), and the scores of the experimental group were significantly lower than those of the control group. It is recommended that in clinical nursing interventions for patients with gastroparesis due to deficiency of spleen and stomach qi, traditional Chinese medicine nursing programs can not only help patients improve clinical nursing effectiveness to a greater extent, but also further help patients alleviate pain levels and improve sleep quality[18-29]. The main reason is that traditional Chinese medicine nursing plans can help patients develop good eating habits, ensure a scientific and reasonable diet, and on the other hand can effectively alleviate the negative emotions of patients[30-38]. On the other hand, it can effectively alleviate the emotional state of patients, enable them to face the disease with positive emotions and cooperate with treatment, thereby improving clinical nursing effectiveness, pain symptoms, and sleep quality[39,40].
This study takes patients with gastric diseases as the research object, and reveals that traditional Chinese medicine nursing has a promoting effect on the rehabilitation of patients with epigastric pain, but the number of cases and treatment methods are still limited. The main reason is that there is no distinction between gastritis patients with all syndromes. In addition, the number of cases is small, which cannot represent all groups, and the detection indicators are limited, which cannot measure changes in all aspects. Therefore, this study will focus on the number of cases, sample size, age group and disease breadth, and use it as a starting point to carry out limited repair experiments.
Comprehensive nursing intervention can maximize the health cognition level of patients, meet the nursing needs of patients, correct wrong cognition, improve patient compliance and improve prognosis by implementing different health education methods and contents at different stages. Comprehensive nursing intervention attaches importance to the implementation of nursing intervention from physiological, psychological and other aspects, attaches importance to the role of psychological factors in the occurrence and development of diseases, strengthens psychological nursing, reduces the negative impact of patients’ stress response on disease recovery, improves treatment compliance to a certain extent, achieves the best treatment and prognosis, and improves the quality of life. However, due to the limitations of research methods, research instruments and sample size, this study cannot represent all groups. It is still necessary to continue to expand the sample size and expand the type of gastritis in order to further promote and make up for these deficiencies.
The TCM care protocol has good clinical application in the clinical care intervention of patients with spleen and stomach gas deficiency type of gastroparesis, with good nursing effect and good improvement in patients’ pain and sleep quality.
Gastroparesis is a common condition in traditional Chinese medicine (TCM), and deficiency of spleen and stomach qi is a frequent symptom. While TCM treatment can improve symptoms, studies suggest that TCM nursing intervention can further enhance efficacy and promote recovery.
To explore the potential benefits of TCM nursing intervention in improving the clinical symptoms of gastroparesis and enhancing patients’ quality of life.
To compare the nursing effects of routine interventions vs TCM procedures on patients with gastroparesis of spleen stomach qi deficiency type, and evaluate the clinical value of TCM nursing intervention in improving pain and sleep quality.
This study selected 80 patients with gastroparesis of spleen stomach qi deficiency type and conducted a randomized controlled trial. The experimental group received TCM nursing procedures, while the control group received routine nursing interventions. The nursing effects of both groups were compared, and changes in symptom scores, pain levels, and sleep quality were observed before and after treatment.
After treatment, the experimental group receiving TCM nursing procedures showed a significantly higher total effective rate compared to the control group (P < 0.05). Additionally, the TCM syndrome scores, visual analogue scale scores, and Pittsburgh sleep quality index scores of the experimental group were significantly lower compared to the control group, with statistical significance (P < 0.05). These findings suggest that TCM nursing has good clinical application value in improving pain and sleep quality in patients with gastroparesis of spleen stomach qi deficiency type.
TCM nursing intervention is an effective clinical nursing option for patients with mild gastroparesis due to spleen and stomach qi deficiency. It has a positive effect on improving pain and sleep quality, and its clinical application value is worth promoting.
Possible future research directions include investigating the long-term effects and mechanisms of TCM nursing intervention for gastroparesis, as well as incorporating objective measures.
Provenance and peer review: Unsolicited article; Externally peer reviewed.
Peer-review model: Single blind
Specialty type: Gastroenterology and hepatology
Country/Territory of origin: China
Peer-review report’s scientific quality classification
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P-Reviewer: Cheng HC, Taiwan; Jeronimo C, Portugal S-Editor: Chen YL L-Editor: A P-Editor: Yuan YY
1. | Wang YY, Yue JR, Xie DM, Carter P, Li QL, Gartaganis SL, Chen J, Inouye SK. Effect of the Tailored, Family-Involved Hospital Elder Life Program on Postoperative Delirium and Function in Older Adults: A Randomized Clinical Trial. JAMA Intern Med. 2020;180:17-25. [PubMed] [DOI] [Cited in This Article: ] [Cited by in Crossref: 60] [Cited by in F6Publishing: 97] [Article Influence: 24.3] [Reference Citation Analysis (0)] |
2. | Chen CC, Li HC, Liang JT, Lai IR, Purnomo JDT, Yang YT, Lin BR, Huang J, Yang CY, Tien YW, Chen CN, Lin MT, Huang GH, Inouye SK. Effect of a Modified Hospital Elder Life Program on Delirium and Length of Hospital Stay in Patients Undergoing Abdominal Surgery: A Cluster Randomized Clinical Trial. JAMA Surg. 2017;152:827-834. [PubMed] [DOI] [Cited in This Article: ] [Cited by in Crossref: 113] [Cited by in F6Publishing: 139] [Article Influence: 19.9] [Reference Citation Analysis (1)] |
3. | Chia-Hui Chen C, Yang YT, Lai IR, Lin BR, Yang CY, Huang J, Tien YW, Chen CN, Lin MT, Liang JT, Li HC, Huang GH, Inouye SK. Three Nurse-administered Protocols Reduce Nutritional Decline and Frailty in Older Gastrointestinal Surgery Patients: A Cluster Randomized Trial. J Am Med Dir Assoc. 2019;20:524-529.e3. [PubMed] [DOI] [Cited in This Article: ] [Cited by in Crossref: 6] [Cited by in F6Publishing: 5] [Article Influence: 0.8] [Reference Citation Analysis (0)] |
4. | Chen CC, Chen CN, Lai IR, Huang GH, Saczynski JS, Inouye SK. Effects of a modified Hospital Elder Life Program on frailty in individuals undergoing major elective abdominal surgery. J Am Geriatr Soc. 2014;62:261-268. [PubMed] [DOI] [Cited in This Article: ] [Cited by in Crossref: 30] [Cited by in F6Publishing: 36] [Article Influence: 3.6] [Reference Citation Analysis (1)] |
5. | Donald GW, Ghaffarian AA, Isaac F, Kraiss LW, Griffin CL, Smith BK, Sarfati MR, Beckstrom JL, Brooke BS. Preoperative frailty assessment predicts loss of independence after vascular surgery. J Vasc Surg. 2018;68:1382-1389. [PubMed] [DOI] [Cited in This Article: ] [Cited by in Crossref: 43] [Cited by in F6Publishing: 55] [Article Influence: 11.0] [Reference Citation Analysis (0)] |
6. | Chen FQ, Leng YF, Ge JF, Wang DW, Li C, Chen B, Sun ZL. Effectiveness of Virtual Reality in Nursing Education: Meta-Analysis. J Med Internet Res. 2020;22:e18290. [PubMed] [DOI] [Cited in This Article: ] [Cited by in Crossref: 184] [Cited by in F6Publishing: 141] [Article Influence: 35.3] [Reference Citation Analysis (0)] |
7. | Zhang YY, Wang ST, Long XH, Wei LH, Pang C, Guan Q, Li QY. Traditional Chinese Nursing Using Fennel With Coarse Salt for Ironing and Umbilical Moxibustion for Epigastric Pain With Spleen-stomach Vacuity Cold. Altern Ther Health Med. 2022;28:88-94. [PubMed] [Cited in This Article: ] |
8. | Wang LN, He W. Nursing experience of abdominal massage intervention for gastrointestinal dysfunction after lung transplantation. Transpl Immunol. 2022;72:101590. [PubMed] [DOI] [Cited in This Article: ] [Cited by in F6Publishing: 2] [Reference Citation Analysis (0)] |
9. | Chen L, Zhou X, Pan Y, Jin L. Observation on the effect of psychological intervention combined with traditional Chinese medicine nursing mode on reducing the adverse reactions of tumor chemotherapy patients. Minerva Pediatr (Torino). 2022;74:815-818. [PubMed] [DOI] [Cited in This Article: ] [Cited by in F6Publishing: 2] [Reference Citation Analysis (0)] |
10. | Zhao Y, Wang C, Dai H. Effects of Rapid Rehabilitation Nursing Based on the Syndrome Differentiation and Treatment Theory of TCM on Sleep and Life Quality of Patients Undergoing Multi-Endoscope Gallbladder-Preserving Cholecystolithotomy. Evid Based Complement Alternat Med. 2022;2022:5339525. [PubMed] [DOI] [Cited in This Article: ] [Cited by in Crossref: 2] [Cited by in F6Publishing: 4] [Article Influence: 2.0] [Reference Citation Analysis (0)] |
11. | Liu M, Tong Y, Chai L, Chen S, Xue Z, Chen Y, Li X. Effects of Auricular Point Acupressure on Pain Relief: A Systematic Review. Pain Manag Nurs. 2021;22:268-280. [PubMed] [DOI] [Cited in This Article: ] [Cited by in Crossref: 4] [Cited by in F6Publishing: 15] [Article Influence: 3.8] [Reference Citation Analysis (0)] |
12. | Gao L, Lv J, Hou L, Yuan Y, Wan Q. Clinical Effects of Chinese Herbal Decoction Combined with Basic Chemoradiotherapy and Nursing Intervention in the Treatment of Cervical Cancer and the Effect on Serum CEA, CA125, and TNF-α Levels. Evid Based Complement Alternat Med. 2021;2021:1446864. [PubMed] [DOI] [Cited in This Article: ] [Cited by in Crossref: 1] [Cited by in F6Publishing: 3] [Article Influence: 1.0] [Reference Citation Analysis (0)] |
13. | Zhang Y, Wang X, Yang H. Effect of traditional Chinese medicine nursing on postoperative patients with gastric cancer and its impact on quality of life. Am J Transl Res. 2021;13:5589-5595. [PubMed] [Cited in This Article: ] |
14. | Borrell-Carrió F, Suchman AL, Epstein RM. The biopsychosocial model 25 years later: principles, practice, and scientific inquiry. Ann Fam Med. 2004;2:576-582. [PubMed] [DOI] [Cited in This Article: ] [Cited by in Crossref: 777] [Cited by in F6Publishing: 615] [Article Influence: 30.8] [Reference Citation Analysis (0)] |
15. | Ma HW, Dan X, Xu SH, Hou RN, Zhao NM. Current status of nurses' perceived professional benefits and influencing factors in 3A-level hospitals in Tianjin. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2017;35:443-447. [PubMed] [DOI] [Cited in This Article: ] [Cited by in F6Publishing: 6] [Reference Citation Analysis (0)] |
16. | Bindman AB, Cox DF. Changes in Health Care Costs and Mortality Associated With Transitional Care Management Services After a Discharge Among Medicare Beneficiaries. JAMA Intern Med. 2018;178:1165-1171. [PubMed] [DOI] [Cited in This Article: ] [Cited by in Crossref: 54] [Cited by in F6Publishing: 66] [Article Influence: 11.0] [Reference Citation Analysis (0)] |
17. | Negewo NA, Gibson PG, McDonald VM. COPD and its comorbidities: Impact, measurement and mechanisms. Respirology. 2015;20:1160-1171. [PubMed] [DOI] [Cited in This Article: ] [Cited by in Crossref: 102] [Cited by in F6Publishing: 168] [Article Influence: 18.7] [Reference Citation Analysis (0)] |
18. | Busca E, Savatteri A, Calafato TL, Mazzoleni B, Barisone M, Dal Molin A. Barriers and facilitators to the implementation of nurse's role in primary care settings: an integrative review. BMC Nurs. 2021;20:171. [PubMed] [DOI] [Cited in This Article: ] [Cited by in Crossref: 2] [Cited by in F6Publishing: 3] [Article Influence: 1.0] [Reference Citation Analysis (0)] |
19. | Newell S, Jordan Z. The patient experience of patient-centered communication with nurses in the hospital setting: a qualitative systematic review protocol. JBI Database System Rev Implement Rep. 2015;13:76-87. [PubMed] [DOI] [Cited in This Article: ] [Cited by in Crossref: 71] [Cited by in F6Publishing: 78] [Article Influence: 13.0] [Reference Citation Analysis (0)] |
20. | Verma N, Buch B, Taralekar R, Acharya S. Diagnostic Concordance of Telemedicine as Compared With Face-to-Face Care in Primary Health Care Clinics in Rural India: Randomized Crossover Trial. JMIR Form Res. 2023;7:e42775. [PubMed] [DOI] [Cited in This Article: ] [Cited by in Crossref: 7] [Reference Citation Analysis (0)] |
21. | Chiang HC, Yang ST, Lee KC, Huang PY, Hsu M, Chang HH. From theory to clinic: key components of qi deficiency in traditional Chinese medicine. Altern Ther Health Med. 2012;18:28-36. [PubMed] [Cited in This Article: ] |
22. | Tang S, Ren J, Kong L, Yan G, Liu C, Han Y, Sun H, Wang XJ. Ephedrae Herba: A Review of Its Phytochemistry, Pharmacology, Clinical Application, and Alkaloid Toxicity. Molecules. 2023;28. [PubMed] [DOI] [Cited in This Article: ] [Cited by in F6Publishing: 19] [Reference Citation Analysis (0)] |
23. | Meng D, Xu G, He L, Zhang M, Padula WV, Davidson PM. Nursing students' perceived value of the work environment: A discrete choice experiment. Geriatr Nurs. 2021;42:94-98. [PubMed] [DOI] [Cited in This Article: ] [Cited by in F6Publishing: 3] [Reference Citation Analysis (0)] |
24. | Pan WW, Lin F, Fort PE. The innate immune system in diabetic retinopathy. Prog Retin Eye Res. 2021;84:100940. [PubMed] [DOI] [Cited in This Article: ] [Cited by in Crossref: 14] [Cited by in F6Publishing: 51] [Article Influence: 17.0] [Reference Citation Analysis (0)] |
25. | Liu Y, Wu N. Progress of Nanotechnology in Diabetic Retinopathy Treatment. Int J Nanomedicine. 2021;16:1391-1403. [PubMed] [DOI] [Cited in This Article: ] [Cited by in Crossref: 36] [Cited by in F6Publishing: 36] [Article Influence: 12.0] [Reference Citation Analysis (0)] |
26. | Kollias AN, Ulbig MW. Diabetic retinopathy: Early diagnosis and effective treatment. Dtsch Arztebl Int. 2010;107:75-83; quiz 84. [PubMed] [DOI] [Cited in This Article: ] [Cited by in Crossref: 50] [Cited by in F6Publishing: 98] [Article Influence: 7.0] [Reference Citation Analysis (0)] |
27. | Liang X, Wang Q, Jiang Z, Li Z, Zhang M, Yang P, Wang X, Wang Y, Qin Y, Li T, Zhang T, Sun J, Li Y, Luo H, Li L. Clinical research linking Traditional Chinese Medicine constitution types with diseases: a literature review of 1639 observational studies. J Tradit Chin Med. 2020;40:690-702. [PubMed] [DOI] [Cited in This Article: ] [Cited by in F6Publishing: 12] [Reference Citation Analysis (0)] |
28. | Su J, Chen L, Song N, Li X, Huang J, Duan P. Auricular Point-Pressing With Bean Plus Esomeprazole Magnesium in Relieving Gastrointestinal Dysfunction. Altern Ther Health Med. 2022;28:16-22. [PubMed] [Cited in This Article: ] |
29. | Li YQ, Zhang CH, Zang CP, Gu SY. Clinical study of Chinese Medicine fumigation combined with "Zhuyuan Decoction" in the treatment of chronic rhinosinusitis. Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020;34:5-9. [PubMed] [DOI] [Cited in This Article: ] [Cited by in F6Publishing: 2] [Reference Citation Analysis (2)] |
30. | Gao L, Huang M, Luo X, Song T, Wang X, Wang Z, Zhang W, Chen J, Lei H. Microstructure abnormity in the optic nerve of type 1 diabetic rats revealed by diffusion tensor imaging study. Magn Reson Imaging. 2020;71:105-114. [PubMed] [DOI] [Cited in This Article: ] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 0.5] [Reference Citation Analysis (0)] |
31. | Tong C, Cao S. Study on the mechanism of visual aging in cats' primary visual cortex based on BDNF-TrkB signal pathway. Sci Rep. 2022;12:10576. [PubMed] [DOI] [Cited in This Article: ] [Reference Citation Analysis (0)] |
32. | Feng Y, Fang Y, Wang Y, Hao Y. Acupoint Therapy on Diabetes Mellitus and Its Common Chronic Complications: A Review of Its Mechanisms. Biomed Res Int. 2018;2018:3128378. [PubMed] [DOI] [Cited in This Article: ] [Cited by in Crossref: 28] [Cited by in F6Publishing: 43] [Article Influence: 7.2] [Reference Citation Analysis (0)] |
33. | Orgah JO, He S, Wang Y, Jiang M, Orgah EA, Duan Y, Zhao B, Zhang B, Han J, Zhu Y. Pharmacological potential of the combination of Salvia miltiorrhiza (Danshen) and Carthamus tinctorius (Honghua) for diabetes mellitus and its cardiovascular complications. Pharmacol Res. 2020;153:104654. [PubMed] [DOI] [Cited in This Article: ] [Cited by in Crossref: 32] [Cited by in F6Publishing: 48] [Article Influence: 12.0] [Reference Citation Analysis (0)] |
34. | Zhang X, Cao D, Yan M, Liu M. The feasibility of Chinese massage as an auxiliary way of replacing or reducing drugs in the clinical treatment of adult type 2 diabetes: A systematic review and meta-analysis. Medicine (Baltimore). 2020;99:e21894. [PubMed] [DOI] [Cited in This Article: ] [Cited by in Crossref: 9] [Cited by in F6Publishing: 8] [Article Influence: 2.0] [Reference Citation Analysis (0)] |
35. | Zhou Y, Li H, Luo L, Chen Y, Chen Q, Bian W, Yang Y, Tang J. Acupoint injection therapy for diabetic retinopathy: A protocol for systematic review and meta-analysis. Medicine (Baltimore). 2021;100:e24119. [PubMed] [DOI] [Cited in This Article: ] [Reference Citation Analysis (0)] |
36. | Wei W, Yang Q, Hu J, Yao Y, Yang H. Dexamethasone-Loaded Injectable In-situ Thermal Crosslinking Magnetic Responsive Hydrogel for the Physiochemical Stimulation of Acupoint to Suppress Pain in Sciatica Rats. Cell Transplant. 2022;31:9636897221126088. [PubMed] [DOI] [Cited in This Article: ] [Cited by in F6Publishing: 3] [Reference Citation Analysis (0)] |
37. | Tian J, Gao Y, Zhang J, Yang Z, Dong S, Zhang T, Sun F, Wu S, Wu J, Wang J, Yao L, Ge L, Li L, Shi C, Wang Q, Li J, Zhao Y, Xiao Y, Yang F, Fan J, Bao S, Song F. Progress and challenges of network meta-analysis. J Evid Based Med. 2021;14:218-231. [PubMed] [DOI] [Cited in This Article: ] [Cited by in Crossref: 3] [Cited by in F6Publishing: 11] [Article Influence: 3.7] [Reference Citation Analysis (0)] |
38. | McBain C, Lawrie TA, Rogozińska E, Kernohan A, Robinson T, Jefferies S. Treatment options for progression or recurrence of glioblastoma: a network meta-analysis. Cochrane Database Syst Rev. 2021;5:CD013579. [PubMed] [DOI] [Cited in This Article: ] [Cited by in Crossref: 37] [Cited by in F6Publishing: 18] [Article Influence: 6.0] [Reference Citation Analysis (0)] |
39. | Hanna C, Lawrie TA, Rogozińska E, Kernohan A, Jefferies S, Bulbeck H, Ali UM, Robinson T, Grant R. Treatment of newly diagnosed glioblastoma in the elderly: a network meta-analysis. Cochrane Database Syst Rev. 2020;3:CD013261. [PubMed] [DOI] [Cited in This Article: ] [Cited by in Crossref: 17] [Cited by in F6Publishing: 19] [Article Influence: 4.8] [Reference Citation Analysis (0)] |
40. | Crider K, Williams J, Qi YP, Gutman J, Yeung L, Mai C, Finkelstain J, Mehta S, Pons-Duran C, Menéndez C, Moraleda C, Rogers L, Daniels K, Green P. Folic acid supplementation and malaria susceptibility and severity among people taking antifolate antimalarial drugs in endemic areas. Cochrane Database Syst Rev. 2022;2. [PubMed] [DOI] [Cited in This Article: ] [Cited by in F6Publishing: 6] [Reference Citation Analysis (0)] |