Synchronous concomitant pancreatic acinar cell carcin and gastric adenocarcinoma: A case report and review of literature

Figure 1 Imaging examinations performed before surgery. On contrast-enhanced computed tomography of stomach, arrow on the left showed uneven thickened with irregular mucosa and heterogeneous contrast enhancement on the antrum of gastric wall; arrow on the right indicated a space-occupying lesion about 34 mm × 16 mm in the tail of the pancreas.

Figure 2 Resection specimen. A: Resection specimen of gastric tumor; B: Resection specimen of pancreatic tumor.

Figure 3 Microscopic examinations of gastric. A: Routine histology, stained using hematoxylin-eosin, shows gastric adenocarcinoma (magnification: × 200); B: Immunohistochemical staining of gastric tumor cells is partial positive for Cytokeratin 7 (magnification: × 200).

Figure 4 Microscopic examinations of pancreas. A: Routine histology, stained using hematoxylin-eosin, shows pancreatic acinar cell adenocarcinoma (magnification: × 200); B: Nuclear division in pancreatic acinar cell carcinoma (magnification: × 400); C: Immunohistochemical staining of pancreatic tumor cells: CAM5.2 expression in pancreatic tumor (magnification: × 200); D: CK19 expression in pancreatic tumor (magnification: × 200); E: Ki-67 partial expression in pancreatic tumor (+ 30%) (magnification: × 200); F: Membranous expression of beta-catenin in pancreatic tumor (magnification: × 200).