Long-term control of melanoma brain metastases with co-occurring intracranial infection and involuntary drug reduction during COVID-19 pandemic: A case report

Figure 1 Timeline of the treatment course of the patient. PFS: Progression-free survival; SRS: Stereotactic radiosurgery.

Figure 2 Representative images of lung and brain metastases in our patient at different stages of treatment. A: Initial lung metastases; B: Progression of lung metastases after 4 mo of progressive disease-1 inhibitor + axitinib treatment; C: Lung metastases eliminated after 19 mo of vemurafenib treatment; D: Metastatic brain lesions before craniotomy; E: Metastatic brain lesions 7 d after craniotomy; F: Progression of brain metastases after 9 mo of vemurafenib + cobimetinib treatment. PD: Progressive disease.