Ghost cell odontogenic carcinoma of the jaws: Report of two cases and a literature review

Figure 1 Cone-beam computed tomography images for case 1. A: Orthopantomographic radiograph showing a round well-defined unilocular radiolucent lesion filling the right maxilla with tooth root resorption and impacted teeth; B: Cone-beam computed tomography image in the coronal plane showing extension of the tumor through the medial and anterior walls of the maxillary sinus.

Figure 2 Histopathological examination in case 1. The tumor nests comprise a well-defined basal layer of columnar cells and cells resembling the stellate reticulum forming an epithelial lining; masses of ghost cells are distributed along with calcification.

Figure 3 Cone-beam computed tomography images for case 2. A: Orthopantomographic radiograph showing a multilocular cyst with ill-defined and extensive bony destructive lesion, with perforation of the buccal and lingual plates of the jaw and infiltration into the soft tissues; B: Cone-beam computed tomography image in the coronal plane showing extension of the tumor and perforation of the buccal and lingual plates of the mandible.

Figure 4 Histopathological examination in case 2. The neoplastic tumor included an epithelial lining showing a basal layer of columnar cells arranged in a palisading pattern and an overlying layer of stratified cells resembling stellate reticulum, with clusters of ghost cells sporadically or intensively distributed in the tumor nests.