Study on gene expression patterns and functional pathways of peripheral blood monocytes reveals potential molecular mechanism of surgical treatment for periodontitis

Figure 1 Clustering module for synergistic expression of genes related to periodontitis. A: According to the co-expression relationship of differentially expressed genes, eight modules are clustered, and one color represents one module; B: Thermogram of modular gene expression in samples. Genes associated with periodontitis are expressed in groups intuitively in disease samples.

Figure 2 Crosstalk relationship between periodontitis modules.

Figure 3 Functional and pathway identification of gene participation in surgical treatment for periodontitis. A: GO functional enrichment analysis of module genes (excerpts). The darker the color, the stronger the significance of enrichment. The larger the circle, the larger the proportion of module genes in GO functional entry genes; B: KEGG pathway enrichment analysis of module genes. The darker the color, the stronger the significance of enrichment. The larger the circle, the larger the proportion of module genes to KEGG pathway entry genes.