Natural killer/T-cell lymphoma with concomitant syndrome of inappropriate antidiuretic hormone secretion: A case report and review of literature

Figure 1 ¹⁸F-fluorodeoxyglucose-positron emission tomography/computed tomography. A: A swollen lymph node in the left submandibular region accompanied by increased fluorodeoxyglucose metabolism; B: Multiple lesions in the skeleton and the abdominal cavity with abnormally high metabolic activity; C: Swelling of the liver and spleen with increased metabolic activity accompanied by nodes with high metabolic activity in the parenchyma.

Figure 2 Histological findings. A and B: Lymph node biopsy showing diffuse infiltration of malignant lymphoid cells (A: HE, ×100, B: ×400). Immunohistochemical staining for (C) CD20(+), (D) CD3(+), and (E) CD56(+) (× 400). F: In situ hybridization showing EBV-encoded small RNA positivity, with most cells showing strongly positive staining (×400). HE: Hematoxylin and eosin; EBV: Epstein-Barr virus.