Immunophenotypic signature of primary glioblastoma multiforme: A case of extended progression free survival

Figure 1 Showing radiological scans and findings. A: Computed tomography (CT) scan at initial diagnosis suggestive of glioma; B: Post-operative image of CT scan with adequate tumor excision and reduced mass effect; C: Magnetic resonance image after 18 mo showing the progressive recurrence of tumor.

Figure 2 Immunofluorescence based immuno-histochemistry analysis and interpretation for human telomerase reverse transcriptase and high mobility group-A1: Control sample showed negative expression of both markers; intense immune-reactivity of high mobility group-A1 and human telomerase reverse transcriptase in Glioblastoma-multiforme and moderate expression in our case.

Figure 3 High mobility group-A1. A: SDS-PAGE protein profile of serum samples; B: Western blot expression for high mobility group-A1 antibody in control serum sample (Con), GBM and present case. GBM: Glioblastoma-multiforme.