Secretory carcinoma of the breast: A case report

Figure 1 Patient’s appearance before treatment. A: Anterolateral projection on the left; B: Anterior projection; C: Anterolateral projection on the right.

Figure 2 Ultrasound of the mammary glands. A: Axial position of th probe; B: Saggital position of the probe. A formation located subareolarly in the right mammary gland (indicated by the arrow).

Figure 3 Magnetic resonance imaging of the mammary glands with intravenous contrast enhancement. A: Direct projection; B: Lateral projection.

Figure 4 Secretory breast cancer. A-C: Polygonal cells with eosinophilic granular or vacuolated cytoplasm, round and oval nuclei [A: Hematoxylin and eosin (H&E), ×10; B: H&E, ×20; C: H&E, ×40].

Figure 5 Secretory breast cancer, histological preparations. A: Positive reaction with estrogen receptors, ×20; B: Expression of Ki 67 in less than 18% of tumor cells, ×20.

Figure 6 Positive reaction with S 100, ×20.

Figure 7 ETV6-NTRK3 gene fusion (marked with arrow).

Figure 8 Macroscopic specimen of the removed sector (the tumor node is indicated by an arrow).

Figure 9 Patient’s appearance 5 months after surgical treatment. A: Anterolateral projection on the left; B: Anterior projection; C: Anterolateral projection on the right.