Aprepitant as add-on to standard antiemetic regimen for concurrent chemoradiotherapy induced nausea vomiting in head and neck cancer

doi:10.12998/wjcc.122960

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Randomized Controlled Trial

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Clin Cases. Aug 16, 2026; 14(23): 122960
Published online Aug 16, 2026. doi: 10.12998/wjcc.122960

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Figure 1 CONSORT chart. ECOG: Eastern Cooperative Oncology Group; CCRT: Concurrent chemoradiotherapy.

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Figure 2 Comparison of complete response rates achieved in the two antiemetic regimen groups. Acute-phase (0-24 hours), delayed-phase (2^nd-5^th day post concurrent chemoradiotherapy). CR: Complete response.

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Figure 3 Comparison of rescue medication use over 5 days post concurrent chemoradiotherapy in both the antiemetic regimen groups. CCRT: Concurrent chemoradiotherapy.

Citation: Gupta N, Sehgal S, Mittal N. Aprepitant as add-on to standard antiemetic regimen for concurrent chemoradiotherapy induced nausea vomiting in head and neck cancer. World J Clin Cases 2026; 14(23): 122960
URL: https://www.wjgnet.com/2307-8960/full/v14/i23/122960.htm
DOI: https://dx.doi.org/10.12998/wjcc.122960