Pegaspargase induced multiple organ failure with acute lymphoblastic leukemia: A case report

Figure 1 Time course of laboratory parameters associated with multiple organ failure after pegaspargase treatment. A: Aspartate aminotransferase (AST) and alanine aminotransferase (ALT); B: Total bilirubin (μmol/L); C: Alkaline phosphatase (ALP) (U/L), γ-Glutamyl transpeptidase (γ-GT) (U/L), and total bile acid (TBA) (μmol/L); D: Glomerular filtration rate (eGFR) (mL/min/1.72 m²); E: Hemoglobin (Hb) (g/L); F: Procalcitonin (PCT) (ng/mL) and C-reactive protein (CRP) (mg/L); G: Prothrombin (PT) time (s) and activated partial thromboplastin time (APTT) (s); H: International normalized ratio (INR); I: Alpha-fetoprotein (AFP) (IU/mL)over time after pegaspargase treatment.