Long-term survival of the Sister Mary Joseph nodule originating from breast cancer: A case report

Figure 1 A 58-year-old woman presented with Sister Mary Joseph's nodule. A and B: A 2-cm hard, localized, and painless nodule with erosions observed in the umbilical region; C: Positron emission tomography (PET) demonstrates increased 18F-fluorodeoxyglucose uptake in the umbilicus, right supraclavicular fossa, and bilateral lung fields (red arrow); D: PET-computed tomography scan revealed increased 18F-fluorodeoxyglucose uptake in the umbilicus (yellow arrow), but there were no nodules or abdominal/pelvic fluid suggesting tumor metastasis to the peritoneum.

Figure 2 Pathology of the metastatic specimens. A: Morphology (Hematoxylin and eosin, × 40); B: Morphology (Hematoxylin and eosin, × 200) confirming an adenocarcinoma in a foamy, tubular arrangement in metastatic lesions.

Figure 3 Perioperative images of tumor resection and immediate abdominal wall reconstruction. A: Tumor excision with a 15 mm horizontal margin, encompassing a combined resection of the peritoneum and the falciform ligament; B: Image showing no exposure of the tumor to the abdominal cavity; C: Macroscopic image of the resected tissue; D–F: Abdominal wall reconstruction using a component-separation technique.

Figure 4 Five-year postoperative images. A: No evident local recurrence in the umbilical region; B: Computed tomography scan shows no nodules, suggesting tumor recurrence in the umbilical region or metastasis to the peritoneum in the abdominal cavity.