First platelet transfusion refractoriness in a patient with acute myelocytic leukemia: A case report

Figure 1 Bone marrow biopsy after admission suggested acute myelocytic leukemia. The relatively active proliferation of bone marrow nucleated cells and the increased ratio of granuloid/erythroid cells. The granuloids are dominated by the cells that are biased towards the naive stage. Immunohistochemistry shows the following: CD34 small blood vessels (+), a large quantity of prokaryotic cells (+), a large quantity of CD117 (+), a large quantity of MPO (+), a large quantity of CD99 (+), TdT (-), a small quantity of CD3 (+), CD79a (-), and lysozyme sporadic (+).

Figure 2 Bone marrow smear shows a myelogram of acute myelocytic leukemia inclined to M2 type. Blood smear: Number of leukocytes is on the large side, and the number of primitive cells accounts for 74%; mature erythrocytes vary in size; a small number of sporadic platelets are visible. Bone marrow smear: Myelogram of acute myelocytic leukemia is inclined to M2 type.

Figure 3 The efficacy of platelet transfusion after myelosuppression caused by the first "IA" chemotherapy. PLT: Platelet.

Figure 4 The efficacy of platelet transfusion after myelosuppression caused by the second cycle of "IA" chemotherapy. PLT: Platelet.