Rare giant corneal keloid presenting 26 years after trauma: A case report

Figure 1 Preoperative clinical appearance and anterior segment optical coherence tomography images. A and B: Slit lamp microscope images; C: Anterior segment optical coherence tomography images.

Figure 2 Surgery procedure. A: Electrocoagulation of the neovascularization on the surface of the swollen tissue; B-C: The hyperplastic fibrous connective tissue was removed, and the corneal stroma was exposed; D: The temporal nutrient vessels were seen in the stroma, with many branches crossing the pupil; E: The corneal stroma was dissected layer-by-layer until the Descemet’s membrane was approached, and the corneal endothelium was transparent; F: A 9.25-mm implant and implant bed were made, and the two were aligned and sutured.

Figure 3 Histopathological and immunohistochemical results. A-B: Hematoxylin and eosin staining showed the irregular surface of the swelling, non-keratinized epithelium without Bowman’s layer, and dense fibrous connective tissue with blood vessels beneath the epithelium; C: Vimentin staining was diffusely positive within the parenchyma of the mass; D: Smooth muscle actin staining was positive in the smooth muscle walls of the vasculature and myofibroblasts.

Figure 4 Postoperative ocular surface and anterior segment optical coherence tomography images. A: Slit lamp image 1 wk after surgery; B: Slit lamp image 4 mo after surgery; C: Anterior segment optical coherence tomography images 4 mo after surgery.