Chondrosarcoma of the toe: A case report and literature review

Figure 1 Computed tomography imaging of chondrosarcoma of the toe. A: Osteochondrosarcoma of the first phalanx of the left foot (arrow) [computed tomography (CT) axial bone window] shows osteolytic destruction of the distal bone of this phalanx; B: Osteochondrosarcoma of the first phalanx of the left foot (arrow) (CT axial soft tissue window) shows the longest diameter of the local soft tissue mass with speckled bony hyperintensity; C: Osteochondrosarcoma of the first phalanx of the left foot (arrow) (CT 3D view) showing osteolytic destruction of the distal bone of this phalanx; D: Osteochondrosarcoma of the first phalanx of the left foot (arrow) (CT sagittal soft tissue window) shows the widest diameter of the local soft tissue mass and the relationship of the lesion to the adjacent phalanx with a speckled bony hyperdense shadow.

Figure 2 Magnetic resonance imaging of chondrosarcoma of the toe. A: T1 weighted imaging shows a low-signal shadow of the mass (arrow); B: The mass enhances heterogeneously and is seen to strengthen with intracompartmental separation-like enhancement and a high-signal shadow distal to the metatarsal bone (arrow).

Figure 3 Pathology of chondrosarcoma of the toe. A: Haematoxylin and eosin-stained section of the tumour (× 20 magnification). Microscopically, there are many slightly heterotopic chondrocytes with large cell densities and binucleated and multinucleated types; B: Haematoxylin and eosin-stained section of the tumour (× 40 magnification). Most of the tumour cells are well differentiated, and some hypertrophic nuclear, large, binucleated cells can be seen in the background of the tumour cartilage tissue, with differing degrees of cell heterogeneity and rare nuclear schizophrenia.

Figure 4 Postoperative photos of the patient. The patient underwent resection of the first phalanx of the left foot + distal bone tumour of the adjacent metatarsal and was followed up for 30 mo after surgery.

Figure 5 Flow diagram of the search process.