Metaplastic breast cancer with chondrosarcomatous differentiation combined with concurrent bilateral breast cancer: A case report

Figure 1 There is a huge mass in the left breast, with local skin cyanosis and varicose veins.

Figure 2 A huge cystic solid mixACed mass. Computed tomography contrast enhancement of the breast.

Figure 3 Core needle biopsy of both breast masses. A: Fine needle aspiration cytology to identify tumor cells (4 × 10); B: An immunohistochemical pathological section of invasive ductal carcinoma in the left breast (4 × 4); C: An immunohistochemical pathological section of invasive ductal carcinoma in the right breast (4 × 10).

Figure 4 After six cycles of neoadjuvant chemotherapy, the tumor shrank significantly. Nuclear magnetic resonance imaging contrast enhancement of the breast.

Figure 5 Immunohistochemical picture of left breast chondrosarcoma component after operation. A: Carcinosarcoma can be found in the invasive ductal carcinoma of the left breast, and the carcinosarcoma is differentiated into chondrosarcoma (4 × 4); B: Vimentin (+) expression was positive (4 × 4).