Copyright
©The Author(s) 2022.
World J Clin Cases. May 26, 2022; 10(15): 4761-4775
Published online May 26, 2022. doi: 10.12998/wjcc.v10.i15.4761
Published online May 26, 2022. doi: 10.12998/wjcc.v10.i15.4761
Figure 1 Distribution of the top 16 somatic mutations in the custom panel.
Figure 2 Distribution of the top 16 somatic mutations in the cBioPortal database.
Figure 3 Type and sites of TP53 mutations.
A: Distribution of TP53 mutation types in the custom panel; B: Distribution of TP53 mutation types in the cBioPortal database; C: Common mutation sites of TP53.
Figure 4 Type and mutation sites of ERBB2.
A: Distribution of ERBB2 mutation types in the custom panel; B: Distribution of ERBB2 mutation types in the cBioPortal database; C: Common mutation sites of ERBB2.
Figure 5 Common mutation sites in the BRCA2, NF1, and PIK3CA genes based on the cBioPortal database.
A: BRCA2; B: NF1; C: PIK3CA.
Figure 6 GO and KEGG enrichment analyses of somatically mutated genes.
A: GO enrichment analysis; B: KEGG enrichment analysis.
Figure 7 Distribution of microsatellite instability in gastric cancer.
A: Distribution of microsatellites in the custom panel; B: Distribution of microsatellites in the cBioPortal database.
- Citation: Zeng HH, Yang Z, Qiu YB, Bashir S, Li Y, Xu M. Detection of a novel panel of 24 genes with high frequencies of mutation in gastric cancer based on next-generation sequencing. World J Clin Cases 2022; 10(15): 4761-4775
- URL: https://www.wjgnet.com/2307-8960/full/v10/i15/4761.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v10.i15.4761