Das D, Ponnampurathu S, Panda PK, Mathuria YP. Different clinical profile of leptospirosis in a tertiary care Indian hospital: A Himalayan experience. World J Clin Cases 2025; 13(25): 106335 [PMID: 40881231 DOI: 10.12998/wjcc.v13.i25.106335]
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05435875
Submitted on:
July 09, 2025, 05:35
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Reader Comments:
tertiary care hospital over the last 7 years from the Himalayan and Sub-Himalayan regions of India.
Studys aim--To analyze the demography, clinical presentation, complications, and mortality risk factors in presumptive leptospirosis patients admitted--- was fulfilled, however, limited to one single center study and observation only.
2018-2024 data were collected based on Modified Faine’s criteria with ELISA diagnosis. \
Sample size is small. 62 number
Study found- equal number of distribution of cases irrespective of sex.
Complications include thrombocytopenia and liver involvement and AKI. MDS was serious complication observed in 66% of cases.
Studies have also highlighted that early administration of antibiotics and aggressive supportive care can improve survival outcomes in critically ill patients with leptospirosis
Limitation—only single center study with possible some selection bias.
Overall Language quality and content-- Excellent.
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