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Manuscript Reader Comments
Shen DX, Wang YW, Lin ZM, Jin D, Ying ZH, Li C. Early screening to identify and diagnose primary nasal tuberculosis in patients with tumor necrosis factor inhibitors. World J Clin Cases 2024; 12(33): 6604-6607 [PMID: 39600487 DOI: 10.12998/wjcc.v12.i33.6604]
Reader's ID:
08068063
Submitted on:
October 02, 2024, 14:26
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Reader Comments:
The article by Shen et al. offers important insights into the need for better screening practices for primary nasal tuberculosis (TB) in patients receiving tumor necrosis factor inhibitor (TNFi) therapy. The rarity of primary nasal TB, due to the nasal mucosa's natural defenses, along with the identified risk factors like diabetes, minimally invasive nasal surgery, and HIV, is well highlighted. We completely agree with the authors about the importance of early detection, especially in high-risk individuals. Their suggestion to increase screening frequency using the Interferon Gamma Release Assay (IGRA) makes sense. However, it’s also worth considering how practical this approach is in areas with lower TB prevalence. In regions with fewer resources, a more targeted strategy based on local TB rates and individual patient risk might be more appropriate. Another point to consider is how clinicians can best decide on the timing of these screenings. While IGRA testing is key, decisions on how often to test should also factor in a patient’s specific history, immune status, and any symptoms they might be experiencing. A one-size-fits-all approach may not work, so a more flexible screening schedule, tailored to both the patient’s needs and the region’s TB prevalence, could be even more effective. We look forward to further research in this area which will help shape future guidelines for managing TB risk in this patient group.
Reply from the Editorial Office:
First, thank you very much for your professional comments on the article published in World Journal of Clinical Cases. Second, we read your comments with great interest. You are welcome to format your valuable comments into a Letter to the Editor and submit it online to World Journal of Clinical Cases at https://www.f6publishing.com. There are no restrictions on the number of words, figures (color, B/W) or authors for a Letter to the Editor. In addition, the article processing charge will be exempted for this Letter to the Editor. As with all articles published by the Baishideng Publishing Group, the Letter to the Editor will be published online after completing peer review. The guidelines for a Letter to the Editor can be found at: https://www.wjgnet.com/bpg/GerInfo/219. Finally, we look forward to receiving your high-quality Letter to the Editor, which will promote academic communication and lead the development of this discipline.