Copyright
©The Author(s) 2024.
World J Methodol. Dec 20, 2024; 14(4): 95598
Published online Dec 20, 2024. doi: 10.5662/wjm.v14.i4.95598
Published online Dec 20, 2024. doi: 10.5662/wjm.v14.i4.95598
Table 1 Hepatocellular carcinoma incidence trends in different age and sex-specific groups across United States geographical regions
Age group, year | Cases (n = 467344)1, (%) | Trends2 | Sex-specific AAPC difference (95%CI)3 | Pairwise comparison P values | ||||
Time period | APC | AAPC | Sex-specific AAPC difference | Coincidence4 | Parallelism5 | |||
West | ||||||||
All ages | ||||||||
Women | 31008 (6.64) | 2001-2014 | 2.66a | 0.96a | -0.02 (-0.86 to 0.82) | 0.95 | < 0.001 | 0.008 |
2014-2020 | -2.61a | |||||||
Men | 84328 (18.04) | 2001-2009 | 4.42a | 0.94a | ||||
2009-2014 | 1.66a | |||||||
2014-2018 | -1.72 | |||||||
2018-2020 | -8.68a | |||||||
Aged ≥ 55 years | ||||||||
Women | 26804 (5.74) | 2001-2014 | 3.10a | 1.36a | 0.61 (-0.42 to 1.65) | 0.24 | < 0.001 | 0.002 |
2014-2020 | -2.30a | |||||||
Men | 68348 (14.62) | 2001-2013 | 4.95a | 1.97a | ||||
2013-2018 | -0.44 | |||||||
2018-2020 | -8.91a | |||||||
Aged < 55 years | ||||||||
Women | 3786 (0.81) | 2001-2009 | 3.26a | -0.78 | -2.15a (-3.65 to -0.64) | 0.005 | < 0.001 | < 0.001 |
2009-2020 | -3.61a | |||||||
Men | 15383 (3.29) | 2001-2004 | 9.67a | -2.92a | ||||
2004-2011 | -1.91a | |||||||
2011-2020 | -7.54a | |||||||
All ages | ||||||||
Women | 3786 (0.810) | 2001-2009 | 3.26a | -0.78 | -2.15a (-3.65 to -0.64) | 0.005 | < 0.001 | < 0.001 |
2009-2020 | -3.61a | |||||||
Men | 15383 (3.291) | 2001-2004 | 9.67a | -2.92a | ||||
2004-2011 | -1.92a | |||||||
2011-2020 | -7.54a | |||||||
Midwest | ||||||||
All ages | ||||||||
Women | 22675 (4.851) | 2001-2017 | 2.42a | 1.12a | 0.50 (-0.54 to 1.55) | 0.34 | < 0.001 | 0.02 |
2017-2020 | -5.56a | |||||||
Men | 61937 (13.252) | 2001-2012 | 3.90a | 1.62a | ||||
2012-2018 | 0.99 | |||||||
2018-2020 | -8.38a | |||||||
Aged ≥ 55 years | ||||||||
Women | 19403 (4.151) | 2001-2017 | 2.82a | 1.53a | 1.12a (0.04 to 2.19) | 0.04 | < 0.001 | < 0.001 |
2017-2020 | -5.08a | |||||||
Men | 51228 (10.961) | 2001-2013 | 4.89a | 2.65a | ||||
2013-2018 | 2.15a | |||||||
2018-2020 | -8.72a | |||||||
Aged < 55 years | ||||||||
Women | 2942 (0.629) | 2001-2010 | 3.02a | -0.35 | -1.61 (-3.57 to 0.36) | 0.10 | < 0.001 | < 0.001 |
2010-2020 | -3.28a | |||||||
Men | 10227 (2.188) | 2001-2003 | 12.75a | -1.95a | ||||
2003-2009 | 0.88 | |||||||
2009-2020 | -5.89a | |||||||
Northeast | ||||||||
All ages | ||||||||
Women | 21729 (4.645) | 2001-2013 | 2.67a | 0.74 | 0.14 (-0.90 to 1.17) | 0.79 | < 0.001 | 0.2 |
2013-2020 | -2.48a | |||||||
Men | 65530 (14.021) | 2001-2007 | 4.77a | 0.88a | ||||
2007-2016 | 1.25a | |||||||
2016-2020 | -5.49a | |||||||
Aged ≥ 55 years | ||||||||
Women | 18703 (4.001) | 2001-2013 | 3.01a | 1.13a | 0.76 (-0.26 to 1.78) | 0.14 | < 0.001 | < 0.001 |
2013-2020 | -2.00a | |||||||
Men | 53688 (11.487) | 2001-2008 | 5.17a | 1.89a | ||||
2008-2016 | 2.62a | |||||||
2016-2020 | -4.97a | |||||||
Aged < 55 years | ||||||||
Women | 2763 (0.591) | 2001-2007 | 6.63a | -0.13 | -3.26a (-5.08 to -1.43) | < 0.001 | < 0.001 | <0.001 |
2007-2020 | -3.10a | |||||||
Men | 11462 (2.452) | 2001-2008 | 2.39a | -3.38a | ||||
2008-2020 | -6.60a | |||||||
South | ||||||||
All ages | ||||||||
Women | 45975 (9.837) | 2001-2015 | 3.74a | 2.08a | 0.46 (-0.53 to 1.45) | 0.36 | < 0.001 | 0.01 |
2015-2020 | -2.42 | |||||||
Men | 134162 (28.707) | 2001-2007 | 6.14a | 2.54a | ||||
2007-2014 | 3.66a | |||||||
2014-2018 | 0.05 | |||||||
2018-2020 | -6.50a | |||||||
Aged ≥ 55 years | ||||||||
Women | 38809 (8.304) | 2001-2016 | 3.99a | 2.53a | 1.12a (0.10 to 2.13) | 0.03 | < 0.001 | < 0.001 |
2016-2020 | -2.77 | |||||||
Men | 108315 (23.176) | 2001-2014 | 5.89a | 3.65a | ||||
2014-2018 | 1.4 | |||||||
2018-2020 | -5.74a | |||||||
Aged < 55 years | ||||||||
Women | 6576 (1.407) | 2001-2009 | 4.77a | 0.5 | -2.01a (-3.77 to -0.24) | 0.02 | < 0.001 | < 0.001 |
2009-2015 | -1.2 | |||||||
2015-2020 | -6.00a | |||||||
Men | 25030 (5.355) | 2001-2006 | 7.81a | -2.05a | ||||
2006-2014 | -2.16a | |||||||
2014-2020 | -9.46a |
- Citation: Abboud Y, Malhotra R, Maan MHA, Mathew A, Abboud I, Pan CW, Alsakarneh S, Jaber F, Mohamed I, Kim D, Pyrsopoulos NT. Hepatocellular carcinoma national burden across different geographical regions in the United States between 2001 and 2020. World J Methodol 2024; 14(4): 95598
- URL: https://www.wjgnet.com/2222-0682/full/v14/i4/95598.htm
- DOI: https://dx.doi.org/10.5662/wjm.v14.i4.95598