Electrolyte-derived clinical indices in traumatic brain injury: A narrative review

doi:10.5662/wjm.v16.i2.111570

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Jun 20, 2026 (publication date) through Apr 23, 2026

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World Journal of Methodology

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2222-0682

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Methodol. Jun 20, 2026; 16(2): 111570
Published online Jun 20, 2026. doi: 10.5662/wjm.v16.i2.111570

Electrolyte-derived clinical indices in traumatic brain injury: A narrative review

Ahammed Mekkodathil, Ayman El-Menyar, Sandro Rizoli, Hassan Al-Thani

Ahammed Mekkodathil, Ayman El-Menyar, Department of Surgery, Trauma and Vascular Surgery, Clinical Research, Hamad Medical Corporation, Doha 3050, Qatar

Ayman El-Menyar, Department of Clinical Medicine, Weill Cornell Medical College, Doha 24144, Qatar

Sandro Rizoli, Hassan Al-Thani, Department of Surgery, Trauma Surgery, Hamad Medical Corporation, Doha 3050, Qatar

Author contributions: Mekkodathil A, El-Menyar A, Rizoli S, and Al-Thani H contributed to the study concept and design; manuscript writing; editing and reviewing the manuscript; All approved the final manuscript.

Conflict-of-interest statement: All authors declare that they have no conflict of interest to disclose.

Corresponding author: Ayman El-Menyar, Professor, Department of Surgery, Hamad Medical Corporation, Al-Rayyan Street, Doha 3050, Qatar. aymanco65@yahoo.com

Received: July 3, 2025
Revised: July 26, 2025
Accepted: October 22, 2025
Published online: June 20, 2026
Processing time: 294 Days and 9.3 Hours

Core Tip

Core Tip: Electrolyte tests are used for monitoring physiological stress in traumatic brain injury. Basic electrolyte calculations assist in evaluating fluid shifts and cerebral edema. This review highlights electrolyte-derived indices to guide management and prognosis. It promotes precision care by emphasizing the use of corrected values. Future research should focus on standardizing these indexes for clinical application.