Systematic Reviews
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Methodol. Jun 20, 2023; 13(3): 127-141
Published online Jun 20, 2023. doi: 10.5662/wjm.v13.i3.127
Acceptability and strategies for enhancing uptake of human immunodeficiency virus self-testing in Nigeria
Victor Abiola Adepoju, Chidinma Umebido, Ademola Adelekan, Ali Johnson Onoja
Victor Abiola Adepoju, Chidinma Umebido, Department of HIV and Infectious Diseases, Self testing in Africa (STAR) Project, Jhpiego Nigeria, Abuja 900901, Federal Capital Territory, Nigeria
Ademola Adelekan, Department of Public Health and Biological Sciences, Blue Gate Research Institute, Ibadan 200116, Oyo State, Nigeria
Ali Johnson Onoja, Department of Research, African Health Project, Abuja 900901, Federal Capital Territory, Nigeria
Author contributions: Adepoju VA and Adelekan A conceived the study; Onoja AJ provided overall guidance to the study; Adelekan A, Umebido C, and Adepoju VA conducted screening and led data extraction; Adelekan A and Onoja AJ drafted the manuscript; All authors read and approved the final version.
Conflict-of-interest statement: All the authors report having no relevant conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ademola Adelekan, DrPH, Researcher, Department of Public Health and Biological Sciences, Blue Gate Research Institute, Ibadan 200116, Oyo State, Nigeria. ademolaadelekan@gmail.com
Received: January 5, 2023
Peer-review started: January 5, 2023
First decision: March 15, 2023
Revised: April 1, 2023
Accepted: April 27, 2023
Article in press: April 27, 2023
Published online: June 20, 2023
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Core Tip

Core Tip: This is the first systematic literature review on the acceptability and uptake of human immunodeficiency virus self-testing (HIVST) in Nigeria. The findings suggested that the acceptability of HIVST is high in Nigeria. However, the actual use of HIVST in programmatic implementation was lower than expected. The use of key opinion leaders among key populations successfully increased the acceptability and uptake of HIVST. However, cost was a major barrier to the acceptability of HIVST. More studies are required to evaluate how the uptake of HIVST compares in routine programs vs real-life settings in the absence of support and resources that enhance HIVST uptake.