Considering mental function for successful total knee arthroplasty in older people

doi:10.5662/wjm.v16.i1.107921

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Mar 20, 2026 (publication date) through Mar 3, 2026

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World Journal of Methodology

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2222-0682

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Methodol. Mar 20, 2026; 16(1): 107921
Published online Mar 20, 2026. doi: 10.5662/wjm.v16.i1.107921

Considering mental function for successful total knee arthroplasty in older people

Takahiko Nagamine

Takahiko Nagamine, Department of Psychiatric Internal Medicine, Sunlight Brain Research Center, Hofu 7470066, Yamaguchi, Japan

Author contributions: Nagamine T carried out all aspects of this manuscript.

Conflict-of-interest statement: The author reports no relevant conflicts of interest for this article.

Corresponding author: Takahiko Nagamine, MD, PhD, Department of Psychiatric Internal Medicine, Sunlight Brain Research Center, 4-13-18 Jiyugaoka, Hofu 7470066, Yamaguchi, Japan. anagamine@yahoo.co.jp

Received: April 2, 2025
Revised: May 10, 2025
Accepted: July 3, 2025
Published online: March 20, 2026
Processing time: 316 Days and 3.9 Hours

Abstract

Many older individuals suffer from chronic knee joint pain due to osteoarthritis, a degenerative joint disease. Total knee arthroplasty (TKA), also known as total knee replacement, is a surgical procedure designed to replace a damaged knee joint with artificial implants. TKA can significantly reduce or eliminate this pain. However, depression or cognitive decline may affect the therapeutic outcome of TKA in older individuals. When performing TKA in older people, it is necessary to screen for and address mental function.

Keywords: Cognitive function; Depression; Older people; Osteoarthritis; Total knee arthroplasty

Core Tip: Depression is indeed common in individuals with osteoarthritis. Depression is not only correlated with sleep disorders, pain, and functional prognosis, but also with cognitive decline. Cognitive decline can be an obstacle to rehabilitation after total knee arthroplasty, leading to a decline in quality of life due to functional decline. Therefore, it’s crucial for healthcare professionals to assess and address both the physical and mental health needs of people with osteoarthritis.