Cardamom extract: An effective weapon in prevention of cardiorenal syndrome induced in rats by cisplatin and high-fat diet

Figure 1 Coronary risk and cardioprotective index of different experimental groups. A: Coronary risk index = T-Ch/HDL-Ch; B: Cardioprotective index = HDL-Ch/LDL-Ch, values are mean ± SE, n = 6, means with different letters show significant difference between values at probability level of 0.05.

Figure 2 Creatine kinase and lactate dehydrogenase as heart function indices in all experimental groups. A: Creatine kinase; B: Lactate dehydrogenase; Values are mean ± SE, n = 6, means with different letters show significant difference between values at probability level of 0.05.

Figure 3 Effect of cardamom extract administration on malondialdehyde and catalase in plasma, heart, and kidney tissues. Values are mean ± SE, n = 6, means with different letters show significant difference between values at probability level of 0.05. MDA: Malondialdehyde; CAT: Catalase.

Figure 4 Effect of cardamom extract administration on plasma inflammatory markers in different groups. A: C-reactive protein; B: Tumor necrosis factor-α; C: Interleukin-6. Values are mean ± SE, n = 6, means with different letters show significant difference between values at probability level of 0.05.

Figure 5 3D and 2D interactions between each compound with large tumor suppressor kinase 1. LATS1: Large tumor suppressor kinase 1.

Figure 6 3D and 2D interactions between each compound with mammalian sterile 20-like kinase 1. MST1: Mammalian sterile 20-like kinase 1.

Figure 7 3D and 2D interactions between each compound with PDZ-binding motif. TAZ: Transcriptional coactivator with PDZ-binding motif.

Figure 8 3D and 2D interactions between each compound with Yes-associated protein. YAP: Yes-associated protein.